HUN-REN Biological Research Centre, Szeged publications

Institute of Biophysics

2023

Barabási B, Barna L, Santa-Maria AR, Harazin A, Molnár R, Kincses A, Vigh, JP, Dukay B, Sántha M, Tóth ME, Walter FR, Deli MA, Hoyk Zs: Role of interleukin-6 and interleukin-10 in morphological and functional changes of the blood-brain barrier in hypertriglyceridemia. Fluids and Barriers of the CNS volume 20, Article number: 15 (2023) https://doi.org/10.1186/s12987-023-00418-3 D1
Bérczi A, Márton Z; Laskay K; Tóth A, Rákhely G, Duzs Á, Sebők‐Nagy K, Páli T, Zimányi L: Spectral and Redox Properties of a Recombinant Mouse Cytochrome b561 Protein Suggest Transmembrane Electron Transfer Function. MOLECULES 28: 5 p. 2261 (2023) https://doi.org/10.1186/s12987-023-00418-3 Q1
Kincses A, Vigh JP, Petrovszki D, Valkai S, Kocsis AE, Walter FR, Lin H-Y, Jan J-S, Deli MA, Dér A: The Use of Sensors in Blood-Brain Barrier-on-a-Chip Devices: Current Practice and Future Directions. BIOSENSORS 13: 3 p. 357 (2023) https://doi.org/10.3390/bios13030357 Q1
Krekic Sz, Mero M, Kuhl M, Balasubramanian K, Dér A, Heiner, Zs: Photoactive Yellow Protein Adsorption at Hydrated Polyethyleneimine and Poly-l-Glutamic Acid Interface. MOLECULES 28: 10 Paper: 4077, 16 p. (2023) https://doi.org/10.3390/molecules28104077 Q1
Krekic Sz, Mero M, Dér A, Heiner Zs: Ultrafast All-Optical Switching Using Doped Chromoprotein Films. JOURNAL OF PHYSICAL CHEMISTRY C 127: 3 pp. 1499-1506., 8 p. (2023) https://doi.org/10.1021/acs.jpcc.2c06232 Q1
Mészáros Á, Molnár K, Fazakas Cs, Nógrádi B, Lüvi A, Dudás T, Tiszlavic Á, Farkas EA, Krizbai IA, Wilhelm I: Inflammasome activation in peritumoral astrocytes is a key player in breast cancer brain metastasis development. ACTA NEUROPATHOLOGICA COMMUNICATIONS 11: 1 Paper: 155, 17 p. (2023) https://doi.org/10.1186/s40478-023-01646-2 D1
Mészáros M, Phan THM, Vigh JP, Porkoláb G, Kocsis A, Páli EK, Polgár TF, Walter FR, Bolognin S, Schwamborn JC, Jan J-S, Deli MA, Veszelka Sz: Targeting Human Endothelial Cells with Glutathione and Alanine Increases the Crossing of a Polypeptide Nanocarrier through a Blood–Brain Barrier Model and Entry to Human Brain Organoid. CELLS 12: 3 Paper: 503, 20 p. (2023) https://doi.org/10.3390/cells12030503 Q1
Misra R, Das I, Dér A, Steinbach G, Shim J-g, Busse W, Jung K-H, Zimányi L, Sheves M: Impact of protein–chromophore interaction on the retinal excited state and photocycle of Gloeobacter rhodopsin: role of conserved tryptophan residues. CHEMICAL SCIENCE 14 pp. 9951-9958., 8 p. (2023) https://doi.org/10.1039/D3SC02961A D1
Nagy Á, Dombi J, Fülep MP, Rudics E, Hompoth EA, Szabó Z, Dér A, Búzás A, Viharos ZsJ, Hoang AT, Maczák B, Vadai G, Gingl Z, László Sz, Bilicki V, Szendi I: SENSORS 23: 2 Paper: 958, 25 p. (2023) https://doi.org/10.3390/s23020958 D1
Pajer K, Bellák T, Grósz T, Nógrádi B, Patai R, Sinkó J, Vinay L, Liabeuf S, Erdélyi M, Nógrádi A: Riluzole treatment modulates KCC2 and EAAT-2 receptor expression and Ca2+ accumulation following ventral root avulsion injury. EUROPEAN JOURNAL OF CELL BIOLOGY 102: 2 Paper: 151317, 14 p. (2023) https://doi.org/10.1016/j.ejcb.2023.151317 D1
Pellicciotta N, Bagal, OS, Sosa, VC, Frangipane G, Vizsnyiczai G, Leonardo RD: Light Controlled Biohybrid Microbots. ADVANCED FUNCTIONAL MATERIALS 33: 39 Paper: 2214801 (2023) https://doi.org/10.1002/adfm.202214801 D1
Petrovszki D, Valkai S, Kelemen L, Nagy L, Agarwal V, Krekic Sz, Zimányi L, Dér A: Microsecond All-Optical Modulation by Biofunctionalized Porous Silicon Microcavity. NANOMATERIALS 13: 14 p. 2070 (2023) https://doi.org/10.3390/nano13142070 Q1
Sebők-Nagy K, Blastyák A, Juhász G, Páli T: Reversible binding of divalent cations to Ductin protein assemblies—A putative new regulatory mechanism of membrane traffic processes. FRONTIERS IN MOLECULAR BIOSCIENCES 10 Paper: 1195010 (2023) https://doi.org/10.3389/fmolb.2023.1195010 Q1
Sebők-Nagy K, Kóta, Z, Kincses A, Fazekas ÁF, Dér A, László Z, Páli T: Spin-Label Electron Paramagnetic Resonance Spectroscopy Reveals Effects of Wastewater Filter Membrane Coated with Titanium Dioxide Nanoparticles on Bovine Serum Albumin. MOLECULES 28: 19 p. 6750 (2023) https://doi.org/10.3390/molecules28196750 Q1
Sipos B, Bella Zs, Gróf I, Veszelka Sz, Deli MA, Szűcs KF, Sztojkov-Ivanov A, Ducza E, Gáspár R, Kecskeméti G, Janáky T, Volk B, Budai-Szűcs M, Ambrus R, Révész P, P Cs I, Katona G: Soluplus® promotes efficient transport of meloxicam to the central nervous system via nasal administration. INTERNATIONAL JOURNAL OF PHARMACEUTICS 632 Paper: 122594, 11 p. (2023) https://doi.org/10.1016/j.ijpharm.2023.122594 D1
Szebenyi Cs, Gu Y, Gebremariam T, Kocsubé S, Kiss-Vetráb S, Jáger O, Patai R, Spisák K, Sinka R, Binder U, Homa M, Vágvölgyi Cs, Ibrahim AS, Nagy G, Pappa T: cotH Genes Are Necessary for Normal Spore Formation andVirulence in Mucor lusitanicus. MBIO 14: 1 Paper: e03386-2, 17 p. (2023) https://doi.org/10.1128/mbio.03386-22 Q1
Szuhaj M, Kakuk B, Wirth R, Rakhely G, Kovacs KL, Bagi Z: Regulation of the methanogenesis pathways by hydrogen at transcriptomic level in time. JOURNAL OF NATURAL PRODUCTS 86: 4 pp. 1074-1080., 7 p. (2023) https://doi.org/10.1007/s00253-023-12700-3 Q1
Tóth G, Santa Maria AR, Herke I, Gáti T, Galvis-Montes D, Walter FR, Deli MA, Hunyadi A: Highly Oxidized Ecdysteroids from a Commercial Cyanotis arachnoidea Root Extract as Potent Blood−Brain Barrier Protective Agents. JOURNAL OF NATURAL PRODUCTS 86: 4 pp. 1074-1080., 7 p. (2023) https://doi.org/10.1021/acs.jnatprod.2c00948 D1
Váradi Gy, Kele Z, Czajlik A, Borics A, Bende G, Papp Cs, Rakhely G, Tóth GK, Batta Gy, Galgóczy, L: Hard nut to crack: Solving the disulfide linkage pattern of the Neosartorya (Aspergillus) fischeri antifungal protein 2. PROTEIN SCIENCE 32: 7 Paper: e4692, 13 p. (2023) https://doi.org/10.1002/pro.4692 D1
Voros C, Bauer D, Migh E, Grexa I, Végh AG, Szalontai B, Castellani, G.; Danka, T.; Dzeroski, S, Koos K, Piccinini F, Horvath P: Correlative Fluorescence and Raman Microscopy to Define Mitotic Stages at the Single-Cell Level: Opportunities and Limitations in the AI Era. BIOSENSORS 13: 2 Paper: 187, 16 p. (2023) https://doi.org/10.3390/bios13020187 Q1

2022

Bashir F, Kovács S, Ábrahám, Á, Nagy K, Ayaydin F, Kelemen-Valkony I, Ferenc Gy, Galajda P, Tóth SzZ, Sass L, Kós P, Vass I, Szabó M: Viable protoplast formation of the coral endosymbiont alga Symbiodinium spp. in a microfluidics platform. LAB ON A CHIP 22(16):2986-2999. https://doi.org/10.1039/d2lc00130f Q1
Boros É, Hegedűs Z, Kellermayer Z, Balogh P, Nagy I: Global alteration of colonic microRNAome landscape associated with inflammatory bowel disease. FRONTIERS IN IMMUNOLOGY 13 Paper: 991346, 14 p. (2022) https://doi.org/10.3389/fimmu.2022.991346 Q1
Buzas A, Horvath T, Der A: A Novel Approach in Heart-Rate-Variability Analysis Based on Modified Poincare Plots. IEEE ACCESS 10 pp. 36606-36615., 10 p. (2022) https://doi.org/10.1109/ACCESS.2022.3162234 Q1
Csoboz B, Gombos I, Kóta Z, Dukic B, Klement É, Varga-Zsíros V, Lipinszki Z, Páli T, Vígh L, Török Z: The Small Heat Shock Protein, HSPB1, Interacts with and Modulates the Physical Structure of Membranes. Int. J. Mol. Sci. 2022, 23, 7317 (2022) https://doi.org/10.3390/ijms23137317 D1
Hudak A, Morgan G, Bacovsky J, Patai R, Polgar TF, Letoha A, Pettko-Szandtner A, Vizler Cs, Szilak L, Letoha T: Biodistribution and Cellular Internalization of Inactivated SARS-CoV-2 in Wild-Type Mice. Int. J. Mol. Sci. 23: 14 Paper: 7609, 17 p. (2022) https://doi.org/10.3390/ijms23147609 D1
Kajner Gy, Kéri A, Bélteki Á, Valkai S, Dér A, Geretovszky Zs, Galbács, G: Multifunctional microfluidic chips for the single particle inductively coupled plasma mass spectrometry analysis of inorganic nanoparticles. LAB ON A CHIP 22: 14 pp. 2766-2776., 11 p. (2022) https://doi.org/10.1039/D2LC00377E D1
Kata D, Grof I, Hoyk Zs, Ducza E, Deli MA, Zupko I, Foldesi I: Immunofluorescent Evidence for Nuclear Localization of Aromatase in Astrocytes in the Rat Central Nervous System. Int. J. Mol. Sci. 23: 16 Paper: 8946, 21 p. (2022) https://doi.org/10.3390/ijms23168946 D1
Menyhart A, Frank R, Farkas AE, Sule Z, Varga VE, Nyul-Toth A, Meiller A, Ivankovits-Kiss O, Lemale CL, Szabo I, Toth R, Zolei-Szenasi D, Woitzik J, Marinesco S, Krizbai IA, Bari F, Dreier JP, Farkas E: Malignant astrocyte swelling and impaired glutamate clearance drive the expansion of injurious spreading depolarization foci. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 42: 4 pp. 584-599., 16 p. (2022) https://doi.org/10.1177/0271678X211040056 D1
Miklovics N, Duzs A, Balogh F, Paragi G, Rakhely G, Toth A: Quinone binding site in a type VI sulfide:quinone oxidoreductase. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 106: 22 pp. 7505-7517., 13 p. (2022) https://doi.org/10.1007/s00253-022-12202-8 Q1
Molnár K, Nógrádi B, Kristóf R, Mészáros Á, Pajer K, Siklós L, Nógrádi A, Wilhelm I, Krizbai IA: Motoneuronal inflammasome activation triggers excessive neuroinflammation and impedes regeneration after sciatic nerve injury. JOURNAL OF NEUROINFLAMMATION 19: 1 Paper: 68, 22 p. (2022) https://doi.org/10.1186/s12974-022-02427-9 D1
Mostafa HIA, Tóth-Boconádi R, Dér L, Fábián L, Taneva SG, Dér A, Keszthelyi L: Nonlinear electric response of the diffuse double layer to an abrupt charge displacement inside a biological membrane. BIOELECTROCHEMISTRY 146 Paper: 108138, 6 p. (2022) https://doi.org/10.1016/j.bioelechem.2022.108138 Q2
Nagy K, Dukic B, Hodula O, Abraham A, Csakvari E, Der L, Wetherington MT, Noorlag J, Keymer JE, Galajda P: Emergence of Resistant Escherichia coli Mutants in Microfluidic On-Chip Antibiotic Gradients. FRONTIERS IN MICROBIOLOGY 13 Paper: 820738, 12 p. (2022) https://doi.org/10.3389/fmicb.2022.820738 Q1
Petrovszki D, Walter FR, Vigh JP, Kocsis A, Valkai S, Deli MA, Dér A: Penetration of the SARS-CoV-2 Spike Protein across the Blood–Brain Barrier, as Revealed by a Combination of a Human Cell Culture Model System and Optical Biosensing. BIOMEDICINES 10: 1 Paper: 188 (2022) https://doi.org/10.3390/biomedicines10010188 Q1
Réthi-Nagy Zs, Ábrahám E, Udvardy K, Klement É, Darula Zs, Pál M, Katona RL, Tubák V, Páli T, Kóta Z, Sinka R, Udvardy A, Lipinszki Z: STABILON, a Novel Sequence Motif That Enhances the Expression and Accumulation of Intracellular and Secreted Proteins. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 23: 15 Paper: 8168, 18 p. (2022) https://doi.org/10.3390/ijms23158168 D1
Szabo K, Varga D, Vegh AG, Liu N, Xiao X, Xu L, Dux L, Erdelyi M, Rovo L, Keller-Pinter A: Syndecan-4 affects myogenesis via Rac1-mediated actin remodeling and exhibits copy-number amplification and increased expression in human rhabdomyosarcoma tumors. CELLULAR AND MOLECULAR LIFE SCIENCES 79: 2 Paper: 122 (2022) https://doi.org/10.1007/s00018-021-04121-0 D1
Széles E, Nagy K, Ábrahám Á, Kovács S, Podmaniczki A, Nagy V, Kovács L, Galajda P, Tóth SzZ: Microfluidic Platforms Designed for Morphological and Photosynthetic Investigations of Chlamydomonas reinhardtii on a Single-Cell Level. CELLS 11: 2 Paper: 285 (2022 https://doi.org/10.3390/cells11020285 Q1
Veszelka Sz, Mészáros M, Porkoláb G, Szecskó A, Kondor N, Ferenc Gy, Polgár TF, Katona G, Kóta Z, Kelemen L, Páli T, Vigh JP, Walter FR, Bolognin S, Schwamborn JC, Jan J-S, Deli MA: A Triple Combination of Targeting Ligands Increases the Penetration of Nanoparticles across a Blood-Brain Barrier Culture Model. PHARMACEUTICS 14: 1 Paper: 86, 19 p. (2022) https://doi.org/10.3390/pharmaceutics14010086 Q1
Walter FR, Harazin A, Toth AE, Veszelka Sz, Santa-Maria AR, Barna L, Kincses A, Biczo G, Balla Z, Kui B, Maleth J, Cervenak L, Tubak V, Kittel A, Rakonczay Zjr, Deli MA: Blood–brain barrier dysfunction in l-ornithine induced acute pancreatitis in rats and the direct effect of l-ornithine on cultured brain endothelial cells. FLUIDS AND BARRIERS OF THE CNS 19: 1 Paper: 16, 20 p. (2022) https://doi.org/10.1186/s12987-022-00308-0 D1
Wetherington MT, Nagy K, Dér L, Ábrahám Á, Noorlag J, Galajda P, Keymer JE: Ecological succession and the competition-colonization trade-off in microbial communities. BMC BIOLOGY 20: 1 Paper: 262 (2022) https://doi.org/10.1186/s12915-022-01462-5 D1
Wetherington MT, Nagy K, Der L, Noorlag J, Galajda P, Keymer J: Variance in Landscape Connectivity Shifts Microbial Population Scaling. FRONTIERS IN MICROBIOLOGY 13 Paper: 831790, 7 p. (2022) https://doi.org/10.3389/fmicb.2022.831790 Q1

2021

Buchroithner, B.; Mayr S.; Hauser, F.; Priglinger, E.; Stangl, H.; Santa-Maria, A. R.; Deli, M. A.; Der, A.; Klar, T. A.; Axmann, M.; Sivun, D.; Mairhofer; M., Jacak, J.: Dual Channel Microfluidics for Mimicking the Blood-Brain Barrier. ACS NANO, 15: 2. 2984-2993. (2021)
Figueira, I.; Galego, S.; Custódio-Santos, T.; Vicente, R.; Molnár, K.; Haskó, J.; Malhó, R.; Videira, M.; Wilhelm, I.; Krizbai, I.; Brito, M. A.: Picturing Breast Cancer Brain Metastasis Development to Unravel Molecular Players and Cellular Crosstalk. CANCERS (Basel), 13: 4. :910. (2021)
Santa-Maria, A. R.; Walter, F. R.; Figueiredo, R.; Kincses, A.; Vigh, J. P.; Heymans, M.; Culot, M.; Winter, P.; Gosselet, F.; Dér, A.;, Deli, M. A.: Flow induces barrier and glycocalyx-related genes and negative surface charge in a lab-on-a-chip human blood-brain barrier model. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2021 Feb 9:271678X21992638. (2021)
Taneva, S. G.; Krumova, S.; Bogár, F.; Kincses, A.; Stoichev, S.; Todinova, S.; Danailova, A.; Horváth, J.; Násztor, Z.; Kelemen, L.; Dér, A.: Insights into graphene oxide interaction with human serum albumin in isolated state and in blood plasma. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 175: pp. 19–29. (2021)
Tóth, R., Farkas, A. E.; Krizbai, I. A.; Makra, P.; Bari, F.; Farkas, E.; Menyhárt, Á.: Astrocyte Ca2+ Waves and Subsequent Non-Synchronized Ca2+ Oscillations Coin

2020

Imre, Norbert ; Hetényi, Anasztázia ; Szabó, Enikő ; Bodnár, Brigitta ; Szkalisity, Abel ; Gróf, Ilona ; Bocsik, Alexandra ; Deli, Mária A. ; Horvath, Peter ; Czibula, Ágnes et al. Routing Nanomolar Protein Cargoes to Lipid Raft‐Mediated/Caveolar Endocytosis through a Ganglioside GM1‐Specific Recognition Tag ADVANCED SCIENCE 7 : 4 Paper: 1902621 , 10 p. (2020)
Vizsnyiczai, G. ; Frangipane, G. ; Bianchi, S. ; Saglimbeni, F. ; Dell’Arciprete, D. ; Di, Leonardo R. A transition to stable one-dimensional swimming enhances E. coli motility through narrow channels NATURE COMMUNICATIONS 11 : 1 Paper: 2340 (2020)
Sereno, Marta ; Haskó, János ; Molnár, Kinga ; Medina, Sarah J ; Reisz, Zita ; Malhó, Rui ; Videira, Mafalda ; Tiszlavicz, László ; Booth, Stephanie A ; Wilhelm, Imola et al. Downregulation of circulating miR 802-5p and miR 194-5p and upregulation of brain MEF2C along breast cancer brain metastasization. MOLECULAR ONCOLOGY 14 : 3 pp. 520-538. , 19 p. (2020)
Varga, Dániel P.; Szabó, Írisz; Varga, Viktória É. ; Menhyárt, Ákos ; M. Tóth, Orsolya ; Kozma, Mihály ; Bálint, Armand R. ; Krizbai, István A. ; Bari, Ferenc ; Farkas, Eszter. The antagonism of prostaglandin FP receptors inhibits the evolution of spreading depolarization in an experimental model of global forebrain ischemia NEUROBIOLOGY OF DISEASE 137 p. 104780 Paper: 104780 (2020)
Bodor, Attila ; Bounedjoum, Naila ; Vincze, Gyorgy Erik ; Erdeine, Kis Agnes ; Laczi, Krisztian ; Bende, Gabor ; Szilagyi, Arpad ; Kovacs, Tamas ; Perei, Katalin ; Rakhely, Gabor Challenges of unculturable bacteria: environmental perspectives REVIEWS IN ENVIRONMENTAL SCIENCE AND BIO-TECHNOLOGY 19 : 1 pp. 1-22. , 22 p. (2020)
Imre, N.; Hetenyi, A.; Szabo, E.; Bodnar, B.; Szkalisity, A.; Grof, I.; Bocsik, A.; Deli, Maria A.; Horvath, P.; Czibula, A.; Monostori, E.; Martinek, T. A.: Routing Nanomolar Protein Cargoes to Lipid Raft‐Mediated/Caveolar Endocytosis through a Ganglioside GM1‐Specific Recognition Tag. ADVANCED SCIENCE, 7: 4 Paper: 1902621, 10 p. (2020)
Vizsnyiczai, G.; Frangipane, G.; Bianchi, S.; Saglimbeni, F.; Dell’Arciprete, D.; Di, Leonardo R.: A transition to stable one-dimensional swimming enhances E. coli motility through narrow channels. NATURE COMMUNICATIONS, 11: 1 Paper: 2340 (2020)
Kincses, A.; Santa-Maria, A. R.; Walter, F. R.; Der, L.; Horányi, N.; Lipka, D. V.; Valkai, S,; Deli, M, A.; Der, A.: A chip device to determine surface charge properties of confluent cell monolayers by measuring streaming potential. LAB ON A CHIP, 20: 20 pp. 3792-3805. 14 p. (2020)
Molnár, K.; Mészáros, Á.; Fazakas, C.; Kozma, M.; Győri, F.; Reisz, Z.; Tiszlavicz, L.; Farkas, A. E.; Nyúl‐Tóth, Á.; Haskó, J.; Krizbai, I. A., Wilhelm, I.: Pericyte‐secreted IGF2 promotes breast cancer brain metastasis formation. MOLECULAR ONCOLOGY, Paper: 1878-0261.12752 (2020)
Bodor, A.; Bounedjoum, N.; Vincze, G. E.; Erdeine Kis, A.; Laczi, K.; Bende, G.; Szilagyi, A.; Kovacs, T.; Perei, K.; Rakhely, G.: Challenges of unculturable bacteria: environmental perspectives. REVIEWS IN ENVIRONMENTAL SCIENCE AND BIO-TECHNOLOGY, 19: 1 pp. 1-22., 22 p. (2020)

2019

Kelemen, L. ; Lepera, E. ; Horvath, B. ; Ormos, P. ; Osellame, R. ; Vazquez, R. Martinez Direct writing of optical microresonators in a lab-on-a-chip for label-free biosensing LAB ON A CHIP 19 : 11 pp. 1985-1990. , 6 p. (2019)
Haskó, János ; Fazakas, Csilla ; Molnár, Kinga ; Mészáros, Ádám ; Patai, Roland ; Szabó, Gábor ; Erdélyi, Ferenc ; Nyúl-Tóth, Ádám ; Győri, Fanni ; Kozma, Mihály et al. Response of the neurovascular unit to brain metastatic breast cancer cells. ACTA NEUROPATHOLOGICA COMMUNICATIONS 7 : 1 Paper: 133,15 p. (2019)
Bocsik, Alexandra ; Gróf, Ilona ; Kiss, Lóránd ; Ötvös, Ferenc ; Zsíros, Ottó ; Daruka, Lejla ; Fülöp, Lívia ; Vastag, Monika ; Kittel, Ágnes ; Imre, Norbert et al. Dual Action of the PN159/KLAL/MAP Peptide: Increase of Drug Penetration across Caco-2 Intestinal Barrier Model by Modulation of Tight Junctions and Plasma Membrane Permeability. PHARMACEUTICS 11 : 2 Paper: 73 , 21 p. (2019)
Herman, Hildegard* ; Fazakas, Csilla* ; Haskó, János ; Molnár, Kinga ; Mészáros, Ádám ; Nyúl-Tóth, Ádám ; Szabó, Gábor ; Erdélyi, Ferenc ; Ardelean, Aurel ; Hermenean, Anca et al. Paracellular and transcellular migration of metastatic cells through the cerebral endothelium JOURNAL OF CELLULAR AND MOLECULAR MEDICINE 23 : 4 pp. 2619-2631. , 13 p. (2019)
Santa-Maria, Ana R ; Walter, Fruzsina R ; Valkai, Sándor ; Brás, Ana Rita ; Mészáros, Mária ; Kincses, András ; Klepe, Adrián ; Gaspar, Diana ; Castanho, Miguel A R B ; Zimányi, László et al. Lidocaine turns the surface charge of biological membranes more positive and changes the permeability of blood-brain barrier culture models. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES 1861 : 9 pp. 1579-1591. , 13 p. (2019)

2018

Bianchi S, Vizsnyiczai G, Ferretti S, Maggi C, Di Leonardo R: An optical reaction micro-turbine. NATURE COMMUNICATIONS, 9:4476(2018)
Wilhelm I, Fazakas C, Molnár K, Végh AG, Haskó J, Krizbai IA: Foe or friend? Janus-faces of the neurovascular unit in the formation of brain metastases. JOURNAL OF CEREBRAL BLOOD FLOW & METABOLISM, 38:563-587(2018)
Sima F, Sugioka K, Vazquez RM, Osellame R, Kelemen L, Ormos P: Three-dimensional femtosecond laser processing for lab-on-a-chip applications. NANOPHOTONICS, 7:613-634(2018)
Hoyk Z, Tóth EM, Lénárt N, Nagy D, Dukay B, Csefová A, Zvara A, Seprényi G, Kincses A, Walter FR, Veszelka S, Vígh J, Barabási B, Harazin A, Kittel A, Puskás LG, Penke B, Vígh L, Deli MA, Sántha M: Cerebrovascular pathology in hypertriglyceridemic APOB-100 transgenic mice. FRONTIERS IN CELLULAR NEUROSCIENCE, 12:380(2018)
Nagy K, Ábrahám A, Keymer JE, Galajda P: Application of microfluidics in experimental ecology: The importance of being spatial. FRONTIERS IN MICROBIOLOGY, 9:496(2018)

2017

Nyúl-Tóth A, Kozma M, Nagyőszi P, Nagy K, Fazakas C, Haskó J, Molnár K, Farkas AE, Végh AG, Váró G, Galajda P, Wilhelm I, Krizbai IA: Expression of pattern recognition receptors and activation of the non-canonical inflammasome pathway in brain pericytes. BRAIN BEHAVIOR AND IMMUNITY 64 PP. 220-231. , 12 P. (2017)
Ferencz M-C, Petrovszki P, Dér A, Sebők-Nagy K, Kóta Z, Páli T: Oscillating electric field measures the rotation rate in a native rotary enzyme. SCIENTIFIC REPORTS, 7:45309(2017)
Patai R, Paizs M, Tortarolo M, Bendotti C, Obál I, Engelhardt JI, Siklós L: Presymptomtically applied AMPA receptor antagonist prevents calcium increase in vulnerable type of motor axon terminals of mce modeling amyotrophic lateral sclerosis. BBA – MOLECULAR BASIS OF DISEASE, 1863:1739-1748(2017)
Béla Varga, Réka Anita Domokos, Csilla Fazakas, Imola Wilhelm, István A. Krizbai, Zsolt Szegletes, Csilla Gergely, György Váró and Attila G. Végh: De-adhesion dynamics of melanoma cells from brain endothelial layer. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1862 : 3 pp. 745-751. , 7 p. (2018)
Heiner Z, Roland T, Leonard J, Haacke S, Groma GI: Kinetics of light-induced intramolceular energy transfer in different conformational states of NADH. JOURNAL OF PHYSICAL CHEMISTRY B 121 : 34 PP. 8037-8045. , 9 P. (2017)

2016

Szuhaj M, Ács N, Tengölics R, Bodor A, Rákhely G, Kovacs KL, Bagi Z: Conversion of H2 and CO2 to CH4 and acetate in fed-batch biogas reactors by mixed biogas community: a novel route for the power-to-gas concept. BIOTECHNOLOGY FOR BIOFUELS, 9:102(2016)
Násztor Z, Bogár F, Dér A: The interfacial tension concept, as revealed by fluctuations. CURRENT OPINION IN COLLOID &INTERFACE SCIENCE, 23:29-40(2016)
Sántha P, Veszelka S, Hoyk Z, Mészáros M, Walter FR, Tóth AE, Kiss L, Kincses A, Oláh Z, Seprényi G, Rákhely G, Dér A, Pákáski M, Kálmán J, Kittel A, Deli MA: Restraint stress-induced morphological changes at the blood-brain barrier in adult rats. FRONTIERS IN MOLECULAR NEUROSCIENCE 8 paper: 88 , 15 P. (2016)
Walter FR, Valkai S, Kincses A, Petneházi A, Czeller T, Veszelka S, Ormos P, Deli MA, Dér A: A versatile lab-on-a-chip tool for modeling biological barriers. SENSORS AND ACTUATORS B: CHEMICAL, 222:1209-1219
Obál I, Klausz G, Mándi Y, Deli M, Siklós L, Engelhardt JI: Intraperitoneally administered IgG from patients with amyotrophic lateral sclerosis or from an immune-mediated goat model increase the levels of TNF-α, IL-6, and IL-10 in the spinal cord and serum of mice. JOURNAL OF NEUROINFLAMMATION, 13:121(2016)

Institute of Biochemistry

2023

Correia-Melo C, Kamrad S, Tengölics R, Messner CB, Trebulle P, Townsend S, Jayasree Varma S, Freiwald A, Heineike BM, Campbell K, Herrera-Dominguez L, Kaur Aulakh S, Szyrwiel L, Yu JSL, Zelezniak A, Demichev V, Mülleder M, Papp B, Alam MT, Ralser M. Cell-cell metabolite exchange creates a pro-survival metabolic environment that extends lifespan. Cell 186, 63–79, January 5, 2023 https://doi.org/10.1016/j.cell.2022.12.007 D1
Zhang S, Wang T, Lima RM, Pettkó-Szandtner A, Kereszt A, Downie JA, Kondorosi E. Widely conserved AHL transcription factors are essential for NCR gene expression and nodule development in Medicago. Nature Plants. doi: 10.1038/s41477-022-01326-4 D1
Nagy LG, Vonk PJ, Künzler M, Földi C, Virágh M, Ohm RA, Hennicke F, Bálint B, Csernetics Á, Hegedüs B, Zhou Z, Liu XB, Nan S, Pareek M, Sahu N, Szathmári B, Varga T, Wu H, Yang X, Merényi Z. Lessons on fruiting body morphogenesis from genomes and transcriptomes of Agaricomycetes. Studies in Mycology https://doi.org/10.3114/sim.2022.104.01 D1
Grézal G, Spohn R, Méhi O, Dunai A, Lázár V, Bálint B, Nagy I, Pál C, Papp B. Plasticity and stereotypic rewiring of the transcriptome upon bacterial evolution of antibiotic resistance. Molecular Biology and Evolution, msad020, https://doi.org/10.1093/molbev/msad020 D1
Apjok G, Számel M, Christodoulou C, Seregi V, Vásárhelyi BM, Stirling T, Eszenyi B, Sári T, Vidovics F, Nagrand E, Kovács D, Szili P, Lantos II, Méhi O, Jangir PK, Herczeg R, Gálik B, Urbán P, Gyenesei A, Draskovits G, Nyerges Á, Fekete G, Bodai L, Zsindely N, Dénes B, Yosef I, Qimron U, Papp B, Pál C, Kintses B. Characterization of antibiotic resistomes by reprogrammed bacteriophage-enabled functional metagenomics in clinical strains. Nature Microbiology (2023). https://doi.org/10.1038/s41564-023-01320-2 D1
Gál L, Bellák T, Marton A, Fekécs Z, Weissman D, Török D, Biju R, Vizler C, Kristóf R, Beattie MB, Lin PJC, Pardi N, Nógrádi A, Pajer K. Restoration of Motor Function through Delayed Intraspinal Delivery of Human IL-10-Encoding Nucleoside-Modified mRNA after Spinal Cord Injury. Research (Wash D C). 2023;6:0056. doi: 10.34133/research.0056 Q1
Verster KI, Cinege G, Lipinszki Z, Magyar LB, Kurucz É, Tarnopol RL, Ábrahám E, Darula Z, Karageorgi M, Tamsil JA, Akalu SM, Andó I, Whiteman NK. Evolution of insect innate immunity through domestication of bacterial toxins. PNAS 120 (16) e2218334120 https://doi.org/10.1073/pnas.221833412 D1
Moshkov N, Becker T, Yang K, Horvath P, Dancik V, Wagner BK, Clemons PA, Singh S, Carpenter AE, Caicedo JC. Predicting compound activity from phenotypic profiles and chemical structures. Nature Communications (2023)14:1967 https://doi.org/10.1038/s41467-023-37570-1 D1
Huszár K, Welker Z, Györgypál Z, Tóth E, Ligeti Z, Kulcsár PI, Dancsó J, Tálas A, Krausz SL, Varga É, Welker E. Position-dependent sequence motif preferences of SpCas9 are largely determined by scaffold-complementary spacer motifs. Nucleic Acids Research, gkad323, https://doi.org/10.1093/nar/gkad323 D1
Sikkema L, Ramírez-Suástegui C, [..], Lung Biological Network Consortium, […], Theis FJ (Lung Biological Network Consortium member: Horváth P). An integrated cell atlas of the lung in health and disease. Nature Medicine (2023). https://doi.org/10.1038/s41591-023-02327-2 D1
Merényi Z, Krizsán K, Sahu N, Liu XB, Bálint B, Stajich JE, Spatafora JW, Nagy LG. Genomes of fungi and relatives reveal delayed loss of ancestral gene families and evolution of key fungal traits. Nature Ecology and Evolution (2023). https://doi.org/10.1038/s41559-023-02095-9 D1
Hirling D, Tasnadi E, Caicedo J, Caroprese MV, Sjögren R, Aubreville M, Koos K, Horvath P. Segmentation metric misinterpretations in bioimage analysis. Nature Methods (2023). https://doi.org/10.1038/s41592-023-01942-8 D1
Pál C, Papp B. How selection shapes the short- and long-term dynamics of molecular evolution. PNAS 2023 Vol. 120 No. 33 e2311012120 https://doi.org/10.1073/pnas.2311012120 D1
Sahu N, Indic B, Wong-Bajracharya J, Merényi Z, Ke HM, Ahrendt S, Monk TL, Kocsubé S, Drula E, Lipzen A, Bálint B, Henrissat B, Andreopoulos B, Martin FM, Bugge Harder C, Rigling D, Ford KL, Foster GD, Pangilinan J, Papanicolaou A, Barry K, LaButti K, Virágh M, […], Sipos G, Plett J, Nagy LG. Nagy. Vertical and horizontal gene transfer shaped plant colonization and biomass degradation in the fungal genus Armillaria. Nature Microbiology (2023). https://doi.org/10.1038/s41564-023-01448-1 D1
Sahu N, Nagy LG. Horizontal gene transfer explains unusual traits of Armillaria fungi. Nature Microbiology 2023 https://doi.org/10.1038/s41564-023-01460-5 D1
Liska O, Boross G, Rocabert C, Szappanos B, Tengölics R, Papp B. Principles of metabolome conservation in animals. PNAS 2023 Aug 29;120(35):e2302147120 https://doi.org/10.1073/pnas.2302147120 D1
Sturm Á, Saskői É, Hotzi B, Tarnóci A, Barna J, Bodnár F, Sharma H, Kovács T, Ari E, Weinhardt N, Kerepesi C, Perczel A, Ivics Z, Vellai T. Downregulation of transposable elements extends lifespan in Caenorhabditis elegans. Nature Communications 14, 5278 (2023). https://doi.org/10.1038/s41467-023-40957-9 D1
Gerber D, Szeifert B, Székely O, Egyed B, Gyuris B, Giblin JI, Horváth A, Köhler K, Kulcsár G, Kustár Á, Major I, Molnár M, Palcsu L, Szeverényi V, Fábián S, Mende BG, Bondár M, Ari E, Kiss V, Szécsényi-Nagy A. Interdisciplinary analyses of Bronze Age communities from Western Hungary reveal complex population histories. Molecular Biology and Evolution, msad182, https://doi.org/10.1093/molbev/msad182 D1
Kulcsár PI, Tálas A, Ligeti Z, Tóth E, Rakvács Z, Bartos Z, Krausz SL, Welker Á, Végi VL, Huszár K, Welker E. A cleavage rule for selection of increased-fidelity SpCas9 variants with high efficiency and no detectable off-targets. Nature Communications 14, 5746 (2023). https://doi.org/10.1038/s41467-023-41393-5 D1
Bukva M, Dobra G, Gyukity-Sebestyen E, Boroczky T, Korsos MM, Meckes DG Jr, Horvath P, Buzas K, Harmati M. (2023). Machine learning-based analysis of cancer cell-derived vesicular proteins revealed significant tumor-specificity and predictive potential of extracellular vesicles for cell invasion and proliferation – A meta-analysis. Cell Commun Signal 21, 333 (2023). https://doi.org/10.1186/s12964-023-01344-5 Q1

2022

Birinyi Zs, Reder D, Diós Á, Korponay-Szabó IR, Hunyadi-Gulyás É, Florides CG, Juhász A, Gell Gy: Immunoanalytic investigation of grain proteins antigenic for celiac disease patients in an einkorn collection. Food Chem. 1 Mar 2022; 371: 131148. doi: 10.1016/j.foodchem.2021.131148. (2022) D1
Boros É, Hegedűs Z, Kellermayer Z, Balogh P, Nagy I: Global alteration of colonic microRNAome landscape associated with inflammatory bowel disease. FRONTIERS IN IMMUNOL. 13 Sept 2022; 13: 991346. doi: 10.3389/fimmu.2022.991346 (2022) Q1
Csabai L, Fazekas D, Kadlecsik T, Szalay-Bekő M, Bohár B, Madgwick M, Módos D, Ölbei M, Gul L, Sudhakar P, Kubisch J, Oyeyemi OJ, Liska O, Ari E, Hotzi B, Billes VA, Molnár E, Földvári-Nagy L, Csályi K, Demeter A, Pápai N, Koltai M, Varga M, Lenti K, Farkas IJ, Türei D, Csermely P, Vellai T, Korcsmáros T: SignaLink3: a multi-layered resource to uncover tissue-specific signaling networks. Nucleic Acids Res. 2022 Jan 7; 50(D1): D701-D709. doi: 10.1093/nar/gkab909. (2022) D1
Dörner K, Badertscher L, Horváth B, Hollandi R, Molnár Cs, Fuhrer T, Meier R, Sárazová M, van den Heuvel J, Zamboni N, Horvath P, Kutay U: Genome-wide RNAi screen identifies novel players in human 60S subunit biogenesis including key enzymes of polyamine metabolism.
Nucleic Acids Res. 21 Mar 2022; 50(5): 2872-2888. doi: 10.1093/nar/gkac072 (2022) D1
Farkas Z, Kovács K, Sarkadi Zs, Kalapis D, Fekete G, Birtyik F, Ayaydin F, Molnár Cs, Horváth P, Pál Cs, Papp B: Gene loss and compensatory evolution promotes the emergence of morphological novelties in budding yeast. Nat Ecol Evol. 28 Apr 2022; 6: 763-773. doi: 10.1038/s41559-022-01730-1. (2022) D1
Hollandi R, Moshkov N, Paavolainen L, Tasnádi E, Piccinini F, Horváth P:
Nucleus segmentation: towards automated solutions. Trends iN Cell Biol. April 2022; 32(4): 295-310; doi: 10.1016/j.tcb.2021.12.004. (2022) D1
Kulcsár PI, Tálas A, Ligeti Z, Krausz SL, Welker E: SuperFi-Cas9 exhibits remarkable fidelity but severely reduced activity yet works effectively with ABE8e. NATURE COMMUN. 11 Nov 2022; 13(1): 6858. doi: 10.1038/s41467-022-34527-8. (2022) D1
Looney B, Miyauchi S, Morin E, Drula E, Courty PE, Kohler A, Kuo A, LaButti K, Pangilinan J, Lipzen A, Riley R, Andreopoulos W, He G, Johnson J, Nolan M, Tritt A, Barry KW, Grigoriev IV, Nagy LG, Hibbett D, Henrissat B, Matheny PB, Labbé J, Martin FM: Evolutionary transition to the ectomycorrhizal habit in the genomes of a hyper-diverse lineage of mushroom-forming fungi. New Phytol. 2021 Dec 3; 233(5): 2294-2309. doi: 10.1111/nph.17892. (2022) D1
Luecken MD, Zaragosi L-E, Madissoon E, Sikkema L, Firsova AB, De Domenico E, Kümmerle L, Saglam A, Berg M, Gay Aurore CA et al.: The discovAIR project: a roadmap towards the Human Lung Cell Atlas. EUR RESPIR J. 18 Aug 2022; 60(2): 2102057. doi: 10.1183/13993003.02057-2021. (2022) D1
Merényi Zs, Virágh M, Gluck-Thaler E, Slot JC, Kiss B, Varga T, Geösel A, Hegedüs B, Bálint B, Nagy LG: Gene age shapes the transcriptional landscape of sexual morphogenesis in mushroom forming fungi (Agaricomycetes). eLife 14 Febr 2022;11:e71348. doi: 10.7554/eLife.71348 (2022) D1
Mishra K, Péter M, Nardiello AM, Keller G, Llado V. Fernandez-Garcia P. Kahlert UD, Barasch D, Saada A, Török Zs, Balogh G, Escriba PV, Piotto S, Kakhlon O: Multifaceted Analyses of Isolated Mitochondria Establish the Anticancer Drug 2-Hydroxyoleic Acid as an Inhibitor of Substrate Oxidation and an Activator of Complex IV-Dependent State 3 Respiration. Cells 7 Feb 2022; 11(3): 578; doi: 10.3390/cells11030578 (2022) Q1
Mund A, Coscia F, Kriston A, Hollandi R, Kovács F, Brunner DA, Migh E, Schweizer L, Santos A, Bzorek M, Naimy S, Rahbek-Gjerdrum LM, Dyring-Andersen B, Bulkescher J, Lukas C, Eckert AM, Lengyel E, Gnann C, Lundberg E, Horvath P, Mann M: Deep Visual Proteomics defines single-cell identity and heterogeneity. NATURE BIOTECHNOL. 14 May 2022; 40: 1231-1240. doi: 10.1038/s41587-022-01302-5. (2022) D1
Pap Á, Király IE, Medzihradszky K, Darula Zs: Multiple Layers of Complexity in O-Glycosylation Illustrated With the Urinary Glycoproteome. MOL CELL PROTEOMICS 21(12): 100439. 16 p. doi: 10.1016/j.mcpro.2022.100439 (2022) D1
Pirhonen J, Szkalisity Á, Hagstrom J, Kim Y, Might E, Kovács M, Holtta M, Peranen J, Seppanen H, Haglund C, Gil J, Rezeli M, Malm J, Horváth P, Markó-Varga Gy, Puolakkainen P, Ikonen E: Lipid Metabolic Reprogramming Extends beyond Histologic Tumor Demarcations in Operable Human Pancreatic Cancer. CANCER RES. 2 Nov 2022 82(21): 3932-3949. doi: 10.1158/0008-5472.CAN-22-0396. (2022) D1
Saado I, Chia K-S, Betz R, Alcantara A, Pettko-Szandtner A, Navarrete F, D'Auria JC, Kolomiets MV, Melzer M, Feussner I, Djamei A: Effector-mediated relocalization of a maize lipoxygenase protein triggers susceptibility to Ustilago maydis. PLANT CELL 5 May 2022; 34(7): 2785-2805. doi: 10.1093/plcell/koac105. (2022) D1
Serra A, Fratello M, Federico A, Ojha R, Provenzani R, Tasnádi E, Cattelani L, del Giudice G, Kinaret PAS, Saarimäki LA, Pavel A, Kuivanen S, Cerullo V, Vapalahti O, Horváth P, Di Lieto A, Yli-Kauhaluoma J, Balistreri G, Greco D: Computationally prioritized drugs inhibit SARS-CoV-2 infection and syncytia formation. Brief Bioinform., Jan 2022; 23(1): bbab507; doi: 10.1093/bib/bbab507:bbab507. (2021) D1
Szádeczky-Kardoss I, Szaker H.M, Verma R, Darkó É, Pettkó-Szandtner A, Silhavy D, Csorba T:
Elongation factor TFIIS is essential for heat stress adaptation in plants. NUCL ACIDS RES. 31 Jan 2022; 50(4): 1927-1950. doi: 10.1093/nar/gkac020. (2022) D1
Tóth EM, Sárközy M, Szűcs G, Dukay B, Hajdu P, Zvara Á, Puskás LG, Szebeni GJ, Ruppert Zs, Csonka Cs, Kovács F, Kriston A, Horváth P, Kővári B, Cserni G, Csont T, Sántha M: Exercise training worsens cardiac performance in males but does not change ejection fraction and improves hypertrophy in females in a mouse model of metabolic syndrome. Biol Sex Differ. 31 Jan 2022; 13: 5. doi: 10.1186/s13293-022-00414-6. (2022) Q1
Virágh M, Merényi Zs, Csernetics Á, Földi Cs, Sahu N, Liu X, Hibbett DS, Nagy LG: Evolutionary Morphogenesis of Sexual Fruiting Bodies in Basidiomycota: Toward a New Evo-Devo Synthesis. MICROBIOL MOL BIOL REVIEWS. March 2022; 86(1): e00019-21. doi: 10.1128/MMBR.00019-21. (2022) Q1
Wu G, Miyauchi S, Morin E, Kuo A, Drula E, Varga T, Kohler A, Feng B, Cao Y, Lipzen A, Daum C, Hundley H, Pangilinan J, Johnson J, Barry K, LaButti K, Ng V, Ahrendt S, Min B, Choi IG, Park H, Plett JM, Magnuson J, Spatafora JW, Nagy LG, Henrissat B, Grigoriev IV, Yang ZL, Xu J, Martin FM: Evolutionary innovations through gain and loss of genes in the ectomycorrhizal Boletales. New Phytol. 2022 Feb; 233(3): 1383-1400. doi: 10.1111/nph.17858. (2022) D1

2021

Dukay B., Walter F.R., Vigh J.P., Barabási B., Hajdu P., Balassa T., Migh E., Kincses A., Hoyk Zs., Szögi T., Borbély E., Csoboz B., Horváth P., Fülöp L., Penke B., Vígh L., Deli M.A., Sántha M., Tóth E.M.: Neuroinflammatory processes are augmented in mice overexpressing human heat-shock protein B1 following ethanol-induced brain injury. J Neuroinflammation. 2021 Jan 10; 18(1): 22. doi.org/10.1186/s12974-020-02070-2. (2021)
Hage H., Miyauchi S., Virágh M., […], Bálint B., Merényi Zs., […], Nagy L.G., Grigoriev I.V., Martin F., Rosso M.-N.: Gene family expansions and transcriptome signatures uncover fungal adaptations to wood decay. Environ Microbiol. 2021, org/10.1111/1462-2920.15423 (2021)
Koós K., Oláh G., Balassa T., Mihut N., Rózsa M., Ozsvár A., Tasnádi E., Barzó P., Faragó N., Puskás L., Molnár G., Molnár J., Tamás G., Horváth P.:
Automatic deep learning-driven label-free image-guided patch clamp system. Nat Commun 12: 936; org/10.1038/s41467-021-21291-4 (2021)
Kovács K., Farkas Z., Bajić D., Kalapis D., Daraba A., Almási K., Kintses B., Bódi Z., Notebaart R.A., Poyatos J.F., Kemmeren P., Holstege F.C.P., Pál Cs., Papp B.: Suboptimal global transcriptional response increases the harmful effects of loss-of-function mutations. BIOL EVOL 2020 Nov 3; 38(3): 1137–1150, doi.org/10.1093/molbev/msaa280 (2021)
Sangeetham S.B., Engelke A.D., Fodor E., Krausz S.L., Tatzelt J., Welker E.: The G127V variant of the prion protein interferes with dimer formationin vitro but not in cellulo. Scientific Reports 2021, 11: 3116; doi.org/10.1038/s41598-021-82647-w (2021)

2020

Kulcsar, P.I.; Talas, A.; Toth, E.; Nyeste, A.; Ligeti, Z.; Welker, Z.; Welker, E.: Blackjack mutations improve the on-target activities of increased fidelity variants of SpCas9 with 5'G-extended sgRNAs. NATURE COMMUNICATIONS, 11: 1, p. 1223. (2020)
Merenyi, Z.; Prasanna, A.N.; Wang, Z.; Kovacs, K.; Hegedus, B.; Balint, B.; Papp, B.; Townsend, J.P.; Nagy, L.G.: Unmatched level of molecular convergence among deeply divergent complex multicellular fungi. MOLECULAR BIOLOGY AND EVOLUTION, (2020)
Moshkov, N.; Mathe, B.; Kertesz-Farkas, A.; Hollandi, R.; Horvath, P.: Test-time augmentation for deep learning-based cell segmentation on microscopy images. SCIENTIFIC REPORTS, 10: 1, p. 5068. (2020)
Vernyik, V.; Karcagi, I.; Timar, E.; Nagy, I.; Gyorkei, A.; Papp, B.; Gyorfy, Z.; Posfai, G.: Exploring the fitness benefits of genome reduction in Escherichia coli by a selection-driven approach. SCIENTIFIC REPORTS, 10: 1, p. 7345. (2020)
Wannier, T.M.; Nyerges, A.; Kuchwara, H.M.; Czikkely, M.; Balogh, D.; Filsinger, G.T.; Borders, N.C.; Gregg, C.J.; Lajoie, M.J.; Rios, X.; Pal, C.; Church, G.M.: Improved bacterial recombineering by parallelized protein discovery. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 117: 24, pp. 13689-13698. (2020)

2019

Balogi, Z.; Multhoff, G.; Jensen, T.K.; Lloyd-Evans, E.; Yamashima, T.; Jaattela, M.; Harwood, J.L.; Vigh, L.: Hsp70 interactions with membrane lipids regulate cellular functions in health and disease. PROGRESS IN LIPID RESEARCH, 74: pp. 18-30. (2019)
Kintses, B.; Mehi, O.; Ari, E.; Szamel, M.; Gyorkei, A.; Jangir, P.K.; Nagy, I.; Pal, F.; Fekete, G.; Tengolics, R.; Nyerges, A.; Liko, I.; Balint, A.; Molnar, T.; Balint, B.; Vasarhelyi, B.M.; Bustamante, M.; Papp, B.; Pal, C.: Phylogenetic barriers to horizontal transfer of antimicrobial peptide resistance genes in the human gut microbiota. NATURE MICROBIOLOGY, 4: 3, pp. 447-458. (2019)
Krizsan, K.; Almasi, E.; Merenyi, Z.; Sahu, N.; Viragh, M.; Koszo, T.; Mondo, S.; Kiss, B.; Balint, B.; Kues, U.; Barry, K.; Cseklye, J.; Hegedus, B.; Henrissat, B.; Johnson, J.; Lipzen, A.; Ohm, R.A.; Nagy, I.; Pangilinan, J.; Yan, J.; Xiong, Y.; Grigoriev, I.V.; Hibbett, D.S.; Nagy, L.G.: Transcriptomic atlas of mushroom development reveals conserved genes behind complex multicellularity in fungi. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 116: 15, pp. 7409-7418. (2019)
Prasanna, A.N.; Gerber, D.; Kijpornyongpan, T.; Aime, M.C.; Doyle, V.P.; Nagy, L.G.: Model Choice, Missing Data, and Taxon Sampling Impact Phylogenomic Inference of Deep Basidiomycota Relationships. SYSTEMATIC BIOLOGY, 69: 1, pp. 17-37. (2019)
Varga, T.; Krizsan, K.; Foldi, C.; Dima, B.; Sanchez-Garcia, M.; Sanchez-Ramirez, S.; Szollosi, G.J.; Szarkandi, J.G.; Papp, V.; Albert, L.; Andreopoulos, W.; Angelini, C.; Antonin, V.; Barry, K.W.; Bougher, N.L.; Buchanan, P.; Buyck, B.; Bense, V.; Catcheside, P.; Chovatia, M.; Cooper, J.; Damon, W.; Desjardin, D.; Finy, P.; Geml, J.; Haridas, S.; Hughes, K.; Justo, A.; Karasinski, D.; Kautmanova, I.; Kiss, B.; Kocsube, S.; Kotiranta, H.; LaButti, K.M.; Lechner, B.E.; Liimatainen, K.; Lipzen, A.; Lukacs, Z.; Mihaltcheva, S.; Morgado, L.N.; Niskanen, T.; Noordeloos, M.E.; Ohm, R.A.; Ortiz-Santana, B.; Ovrebo, C.; Racz, N.; Riley, R.; Savchenko, A.; Shiryaev, A.; Soop, K.; Spirin, V.; Szebenyi, C.; Tomsovsky, M.; Tulloss, R.E.; Uehling, J.; Grigoriev, I.V.; Vagvolgyi, C.; Papp, T.; Martin, F.M.; Miettinen, O.; Hibbett, D.S.; Nagy, L.G.: Megaphylogeny resolves global patterns of mushroom evolution. NATURE ECOLOGY AND EVOLUTION, 3: 4, pp. 668-678. (2019)

2018

Carragher, N.; Piccinini, F.; Tesei, A.; Trask, O.J., Jr.; Bickle, M.; Horvath, P.: Concerns, challenges and promises of high-content analysis of 3D cellular models. NATURE REVIEWS: DRUG DISCOVERY, 17: 8, p. 606. (2018)
Lazar, V.; Martins, A.; Spohn, R.; Daruka, L.; Grezal, G.; Fekete, G.; Szamel, M.; Jangir, P.K.; Kintses, B.; Csorgo, B.; Nyerges, A.; Gyorkei, A.; Kincses, A.; Der, A.; Walter, F.R.; Deli, M.A.; Urban, E.; Hegedus, Z.; Olajos, G.; Mehi, O.; Balint, B.; Nagy, I.; Martinek, T.A.; Papp, B.; Pal, C.: Antibiotic-resistant bacteria show widespread collateral sensitivity to antimicrobial peptides. NATURE MICROBIOLOGY, 3: 6, pp. 718-731. (2018)
Nyerges, A.; Csorgo, B.; Draskovits, G.; Kintses, B.; Szili, P.; Ferenc, G.; Revesz, T.; Ari, E.; Nagy, I.; Balint, B.; Vasarhelyi, B.M.; Bihari, P.; Szamel, M.; Balogh, D.; Papp, H.; Kalapis, D.; Papp, B.; Pal, C.: Directed evolution of multiple genomic loci allows the prediction of antibiotic resistance. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 115: 25, pp. E5726-E5735. (2018)
Sipos, G.; Anderson, J.B.; Nagy, L.G.: Armillaria. CURRENT BIOLOGY, 28: 7, pp. R297-R298. (2018)
Toth, E.; Czene, B.C.; Kulcsar, P.I.; Krausz, S.L.; Talas, A.; Nyeste, A.; Varga, E.; Huszar, K.; Weinhardt, N.; Ligeti, Z.; Borsy, A.E.; Fodor, E.; Welker, E.: Mb- and FnCpf1 nucleases are active in mammalian cells: activities and PAM preferences of four wild-type Cpf1 nucleases and of their altered PAM specificity variants. NUCLEIC ACIDS RESEARCH, 46: 19, pp. 10272-10285. (2018)

2017

Bodi, Z.; Farkas, Z.; Nevozhay, D.; Kalapis, D.; Lazar, V.; Csorgo, B.; Nyerges, A.; Szamecz, B.; Fekete, G.; Papp, B.; Araujo, H.; Oliveira, J.L.; Moura, G.; Santos, M.A.S.; Szekely, T., Jr.; Balazsi, G.; Pal, C.: Phenotypic heterogeneity promotes adaptive evolution. PLOS BIOLOGY, 15: 5, p. e2000644. (2017)
Kulcsar, P.I.; Talas, A.; Huszar, K.; Ligeti, Z.; Toth, E.; Weinhardt, N.; Fodor, E.; Welker, E.: Crossing enhanced and high fidelity SpCas9 nucleases to optimize specificity and cleavage. GENOME BIOLOGY, 18: 1, p. 190. (2017)
Montiel, J.; Downie, J.A.; Farkas, A.; Bihari, P.; Herczeg, R.; Balint, B.; Mergaert, P.; Kereszt, A.; Kondorosi, E.: Morphotype of bacteroids in different legumes correlates with the number and type of symbiotic NCR peptides. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 114: 19, pp. 5041-5046. (2017)
Piccinini, F.; Balassa, T.; Szkalisity, A.; Molnar, C.; Paavolainen, L.; Kujala, K.; Buzas, K.; Sarazova, M.; Pietiainen, V.; Kutay, U.; Smith, K.; Horvath, P.: Advanced Cell Classifier: User-Friendly Machine-Learning-Based Software for Discovering Phenotypes in High-Content Imaging Data. CELL SYSTEMS, 4: 6, pp. 651-655 e655. (2017)
Sipos, G.; Prasanna, A.N.; Walter, M.C.; O'Connor, E.; Balint, B.; Krizsan, K.; Kiss, B.; Hess, J.; Varga, T.; Slot, J.; Riley, R.; Boka, B.; Rigling, D.; Barry, K.; Lee, J.; Mihaltcheva, S.; LaButti, K.; Lipzen, A.; Waldron, R.; Moloney, N.M.; Sperisen, C.; Kredics, L.; Vagvolgyi, C.; Patrignani, A.; Fitzpatrick, D.; Nagy, I.; Doyle, S.; Anderson, J.B.; Grigoriev, I.V.; Guldener, U.; Munsterkotter, M.; Nagy, L.G.: Genome expansion and lineage-specific genetic innovations in the forest pathogenic fungi Armillaria. NATURE ECOLOGY AND EVOLUTION, 1: 12, pp. 1931-1941. (2017)

2016

Horvath, P.; Aulner, N.; Bickle, M.; Davies, A.M.; Nery, E.D.; Ebner, D.; Montoya, M.C.; Ostling, P.; Pietiainen, V.; Price, L.S.; Shorte, S.L.; Turcatti, G.; von Schantz, C.; Carragher, N.O.: Screening out irrelevant cell-based models of disease. NATURE REVIEWS: DRUG DISCOVERY, 15: 11, pp. 751-769. (2016)
Karcagi, I.; Draskovits, G.; Umenhoffer, K.; Fekete, G.; Kovacs, K.; Mehi, O.; Baliko, G.; Szappanos, B.; Gyorfy, Z.; Feher, T.; Bogos, B.; Blattner, F.R.; Pal, C.; Posfai, G.; Papp, B.: Indispensability of Horizontally Transferred Genes and Its Impact on Bacterial Genome Streamlining. MOLECULAR BIOLOGY AND EVOLUTION, 33: 5, pp. 1257-1269. (2016)
Nyerges, A.; Csorgo, B.; Nagy, I.; Balint, B.; Bihari, P.; Lazar, V.; Apjok, G.; Umenhoffer, K.; Bogos, B.; Posfai, G.; Pal, C.: A highly precise and portable genome engineering method allows comparison of mutational effects across bacterial species. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 113: 9, pp. 2502-2507. (2016)
Papp, B.; Lazar, V.: Antibiotics: New recipe for targeting resistance. NATURE CHEMICAL BIOLOGY, 12: 11, pp. 891-892. (2016)
Szappanos, B.; Fritzemeier, J.; Csorgo, B.; Lazar, V.; Lu, X.; Fekete, G.; Balint, B.; Herczeg, R.; Nagy, I.; Notebaart, R.A.; Lercher, M.J.; Pal, C.; Papp, B.: Adaptive evolution of complex innovations through stepwise metabolic niche expansion. NATURE COMMUNICATIONS, 7: p. 11607. (2016)

Institute of Genetics

2023

Boda A, Varga LP, Nagy A, Szenci G, Csizmadia T, Lőrincz P, Juhász G.: Rab26 controls secretory granule maturation and breakdown in Drosophila. CELLULAR AND MOLECULAR LIFE SCI. 80:1 Paper: 24, 15 p. (2023) https://doi.org/10.1111/fwb.14168 D1
Cinege G, Magyar LB, Kovács H, Varga V, Bodai L, Zsindely N, Nagy G, Hegedűs Z, Hultmark D**, Andó I.: Distinctive features of Zaprionus indianus hemocyte differentiation and function revealed by transcriptomic analysis. FRONTIERS IN IMMUNOLOGY 14 Paper: 1322381, 14 p. (2023) https://doi.org/10.3389/fimmu.2023.1322381 Q1
Czimmerer Z, Nagy L.: Epigenomic regulation of macrophage polarization: Where do the nuclear receptors belong? IMMUNOLOGICAL REVIEWS 14 p. (2023) https://doi.org/10.1111/imr.13209 D1
Dániel B, Belk JA, Meier SL, Chen AZ, Sándor K, Czimmerer Z, Varga Z, Bene K, Buquicchio FA, Qi Y, Satpathy AT et al.: Macrophage inflammatory and regenerative response periodicity is programmed by cell cycle and chromatin state. MOLECULAR CELL 83:1 pp. 121-138 e7. (2023) https://doi.org/10.1016/j.molcel.2022.11.017 D1
Domokos A, Varga Z*, Jambrovics K, Caballero-Sánchez N, Szabó E, Nagy G, Scholtz B, Halász L, Váradi E, Bene KP, Mázló A, Bacsi A, Jeney V, Szebeni GJ, Nagy L, Czimmerer Z.: The transcriptional control of the VEGFA-VEGFR1 (FLT1) axis in alternatively polarized murine and human macrophages. FRONTIERS IN IMMUNOLOGY 14 Paper: 1168635 (2023) https://doi.org/10.3389/fimmu.2023.1168635 Q1
Gazsó-Gerhát G, Gombos R*, Tóth K, Kaltenecker P, Szikora S, Bíró J, Csapó E, Asztalos Z, Mihály J.: FRL and DAAM are required for lateral adhesion of interommatidial cells and patterning of the retinal floor. DEVELOPMENT 150:22 Paper: dev. 201713 (2023) https://doi.org/10.1242/dev.201713 D1
González Morales N, Marescal O, Szikora S, Katzemich A, Correia-Mesquita T, Bíró P, Erdélyi M, Mihály J, Schöck F.: The oxoglutarate dehydrogenase complex is involved in myofibril growth and Z-disc assembly in Drosophila. JOURNAL OF CELL SCIENCE 136:13 Paper: jcs260717, 12 p. (2023) https://doi.org/10.1242/jcs.260717 Q1
Henry S, Kókity L, Pirity MK.: Polycomb protein RYBP activates transcription factor Plagl1 during in vitro cardiac differentiation of mouse embryonic stem cells. OPEN BIOLOGY 13:2 Paper: 20305, 20 p. (2023) https://doi.org/10.1098/rsob.220305 D1
Imre G, Takács B*, Czipa E, Bakné Drubi A, Jaksa G, Latinovics D, Nagy A, Karkas R, Hudoba L, Vásárhelyi BM, Mátés L et al.: Prolonged activity of the transposase helper may raise safety concerns during DNA transposon-based gene therapy. MOLECULAR THERAPY-METHODS AND CLINICAL DEVELOPMENT 29 pp. 145-159., 15 p. (2023) https://doi.org/10.1016/j.omtm.2023.03.003 Q1
Jipa A, Juhász G.: Disagreement among the three musketeers of the unfolded protein response. JOURNAL OF CELL BIOLOGY 222:5 Paper: e202304013 (2023) https://doi.org/10.1083/jcb.202304013 D1
Kúthy-Sutus E, Kharrat B, Gábor E, Csordás G, Sinka R, Honti V.: A Novel Method for Primary Blood Cell Culturing and Selection in Drosophila melanogaster. CELLS 12:1 p. 24 (2023) https://doi.org/10.3390/cells12010024 Q1
Longarini EJ, Dauben H, Locatelli C, Wondisford AR, Smith R, Fajka-Boja R, Schuller M, Ahel I, Timinszky G, Huet S, Matic I et al.: Modular antibodies reveal DNA damage-induced mono-ADP-ribosylation as a second wave of PARP1 signaling. MOLECULAR CELL 83:10 pp. 1743-1760.e11. (2023) https://doi.org/10.1016/j.molcel.2023.03.027 D1
Maruzs T, Feil-Börcsök D*, Lakatos E, Juhász G, Blastyák A, Hargitai D, Jean S, Lőrincz P, Juhász G.: Interaction of the sorting nexin 25 homolog Snazarus with Rab11 balances endocytic and secretory transport and maintains the ultrafiltration diaphragm in nephrocytes MOLECULAR BIOLOGY OF THE CELL (2023) https://doi.org/10.1091/mbc.E22-09-0421 Q1
Pekker E, Priskin K, Szabó-Kriston É, Csányi B, Buzás-Bereczki O, Adorján L, Szukacsov V, Haracska L et al.: Development of a Large-Scale Pathogen Screening Test for the Biosafety Evaluation of Canine Mesenchymal Stem Cells. BIOLOGICAL PROCEDURES ONLINE 25:1 Paper: 33, 14 p. (2023) https://doi.org/10.1186/s12575-023-00226-x Q1
Smith R, Zentout S, Rother M, Bigot N, Chapuis C, Mihut A, Zobel FF, Ahel I, van Attikum H, Timinszky G, Huet S.: HPF1-dependent histone ADP-ribosylation triggers chromatin relaxation to promote the recruitment of repair factors at sites of DNA damage. NATURE STRUCTURAL & MOLECULAR BIOLOGY 35 p. (2023) https://doi.org/10.1038/s41594-023-00977-x D1
Szabó Á, Vincze V*, Sanjay Chhatre A*, Jipa A, Bognár S, Varga K, Banik P, Harmatos-Ürmösi A, Neukomm L, Juhász G.: LC3-associated phagocytosis promotes glial degradation of axon debris after injury in Drosophila models. NATURE COMMUNICATIONS (2023) https://doi.org/10.1038/s41467-023-38755-4 D1
Szenci G, Csizmadia T, Juhász G.: The role of crinophagy in quality control of the regulated secretory pathway. JOURNAL OF CELL SCIENCE 136:8 Paper: jcs260741 (2023) https://doi.org/10.1242/jcs.260741 Q1
Varga D, Szikora S, Novák T, Pap G, Lékó G, Mihály J, Erdélyi M.: Machine learning framework to segment sarcomeric structures in SMLM data. SCIENTIFIC REPORTS 13:1 Paper: 1582, 10 p. (2023) https://doi.org/10.1038/s41598-023-28539-7 D1
Vedelek V, Vedelek B, Lőrincz P, Juhász G, Sinka R.: A comparative analysis of fruit fly and human glutamate dehydrogenases in Drosophila melanogaster sperm development. FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY 11 p. 10.3389/fcell.2023.1281487 (2023) https://doi.org/10.3389/fcell.2023.1281487 Q1
Verster KI, Cinege G*, Lipinszki Z, Magyar LB, Kurucz É, Tarnopol RL, Ábrahám E, Darula Z, Karageorgi M, Tamsil JA, Akalu SM, Andó I, Whiteman NK.: Evolution of insect innate immunity through domestication of bacterial toxins. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 120:16 (2023) https://doi.org/10.1073/pnas.2218334120 D1

2022

Ábrahám A, Villányi Z, Zsindely N, Nagy G, Szabó Á, Bodai L, Henn L, Boros I.: Despite its sequence identity with canonical H4, Drosophila H4r product is enriched at specific chromatin regions. SCIENTIFIC REPORTS 12:1 Paper: 5007, 11 p. (2022) https://doi.org/10.1038/s41598-022-09026-x D1
Bálint É, Unk I.: Manganese is a strong specific activator of the rna synthetic activity of human polη. INTERNATIONAL JOURNAL OF MOL. SCI. 23:1 Paper: 230 (2022) https://doi.org/10.3390/ijms23010230 D1
Bhattacharjee A, Ürmösi A, Jipa A, Kovács L, Deák P, Szabó Á, Juhász G.: Loss of ubiquitinated protein autophagy is compensated by persistent cnc/NFE2L2/Nrf2 antioxidant responses. AUTOPHAGY 18:10 pp. 2385-2396., 12 p. (2022) doi: 10.1080/15548627.2022.2037852 D1
Borkúti P, Kristó I, Szabó A, Bajusz C, Kovács Z, Réthy-Nagy Z, Lipinszki Z, Lukacsovich T, Bogdan S, Vilmos P.: Parallel import mechanisms ensure the robust nuclear localization of actin in Drosophila. FRONTIERS IN MOL. BIOSCIENCES 9 Paper: 963635, 16 p. (2022) https://doi.org/10.3389/fmolb.2022.963635 Q1
Cinege G, Magyar LB, Kovács AL, Lerner Z, Juhász G, Lukacsovich D, Winterer J, Lukacsovich T, Hegedűs Z, Kurucz É, Hultmark D, Földy C, Andó I.: Broad Ultrastructural and Transcriptomic Changes Underlie the Multinucleated Giant Hemocyte Mediated Innate Immune Response against Parasitoids. JOURNAL OF INNATE IMMUNITY 14:4 pp. 335-354., 20 p. (2022) https://doi.org/10.1159/000520110 Q1
Czimmerer Z, Halász L, Dániel B, Varga Z, Bene K, Domokos A, Hoeksema M, Shen Z, Berger WK, Cseh T, Jambrovics K, Kolostyák Z, Fenyvesi F, Váradi J, Poliska S, Hajas G, Szatmári I, Glass CK, Bacsi A, Nagy A.: The epigenetic state of IL-4-polarized macrophages enables inflammatory cistromic expansion and extended synergistic response to TLR ligands. IMMUNITY 55:11 pp. 2006-2026.e6. (2022) https://doi.org/10.1016/j.immuni.2022.10.004 D1
Fenteany G, Sharma G, Gaur P, Borics A, Wéber E, Kiss E, Haracska L.: A series of xanthenes inhibiting Rad6 function and Rad6–Rad18 interaction in the PCNA ubiquitination cascade. ISCIENCE 104053: 4 p. 104053 Paper (2022) https://doi.org/10.1016/j.isci.2022.104053 D1
Hultmark D, Andó I.: Hematopoietic plasticity mapped in Drosophila and other insects. ELIFE 11 p. e78906 (2022) https://doi.org/10.7554/eLife.78906 D1
Kharrat B, Csordás G, Honti V.: Peeling Back the Layers of Lymph Gland Structure and Regulation. INTERNATIONAL JOURNAL OF MOL. SCI. 23:14 7767-7767. Paper: 7767, 16 p. (2022) https://doi.org/10.3390/ijms23147767 D1
Kopasz AG, Pusztai DZ*, Karkas R, Hudoba L, Abdullah KSA, Imre G, Pankotai-Bodó G, Migh E, Nagy A, Kriston A, Germán P, Bakné Drubi A, Molnár A, Fekete I, Dani VÉ, Ocsovszki I, Puskás LG, Horváth P, Sükösd F, Mátés L.: A versatile transposon-based technology to generate loss- and gain-of-function phenotypes in the mouse liver. BMC BIOLOGY 20:1 Paper: 74 16 p. (2022) https://doi.org/10.1186/s12915-022-01262-x D1
Maróti Z, Neparáczki E, Schütz O, Maár K, Raskó I. et al.: The genetic origin of Huns, Avars, and conquering Hungarians. CURRENT BIOLOGY 32:13 pp. 2858-2870., 13 p. (2022) https://doi.org/10.1016/j.cub.2022.04.093 D1
McMahon M, O’Dell G, Tan J, Sárközy A, Vadovics M, Carreno JM, Puente-Massaguer E, Muramatsu H, Bajusz C, Rijnink W, Beattie M, Tam YK, Kirkpatrick Roubidoux E, Fransisco I, Strohmeier S, Kanekiyo M, Graham BS, Krammer F, Pardi N.: Assessment of a quadrivalent nucleoside-modified mRNA vaccine that protects against group 2 influenza viruses. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE USA 119:45 Paper: e2206333119 (2022) https://doi.org/10.1073/pnas.2206333119 D1
Muramatsu H, Lam K, Bajusz C, Laczkó D, Karikó K, Schreiner P, Martin A, Lutwyche P, Heyes J, Pardi N.: Lyophilization provides long-term stability for a lipid nanoparticle-formulated , nucleoside-modified mRNA vaccine. MOLECULAR THERAPY 30:5 pp. 1941-1951., 11 p. (2022) https://doi.org/10.1016/j.ymthe.2022.02.001 D1
Pardi N, Carreno JM, O’Dell G, Tan J, Bajusz C, Muramatsu H, Rijnink W, Strohmeier S. et al.: Development of a pentavalent broadly protective nucleoside-modified mRNA vaccine against influenza B viruses. NATURE COMMUNICATIONS 13:1 Paper: 4677, 14 p. (2022) https://doi.org/10.1038/s41467-022-32149-8 D1
Qorri E, Takács B, Gráf A, Enyedi MZ, Pintér L, Kiss E, Haracska L.: A Comprehensive Evaluation of the Performance of Prediction Algorithms on Clinically Relevant Missense Variants. INTERNATIONAL JOURNAL OF MOL. SCI. 23:14 p. 7946 (2022) https://doi.org/10.3390/ijms23147946 D1
Rahman A, Lőrincz P, Gohel R, Nagy A, Csordás G, Zhang Y, Juhász G, Nezis IP.: GMAP is an Atg8a-interacting protein that regulates Golgi turnover in Drosophila. CELL REPORTS 39:9 p. 110903 (2022) https://doi.org/10.1016/j.celrep.2022.110903 D1
Sutus E, Henry S, Adorján L, Kovács G, Pirity MK.: RYBP regulates Pax6 during in vitro neural differentiation of mouse embryonic stem cells. SCIENTIFIC REPORTS 12:1 Paper: 2364 (2022) https://doi.org/10.1038/s41598-022-06228-1 D1
Szikora S, Görög P, Mihály J.: The Mechanisms of Thin Filament Assembly and Length Regulation in Muscles. INTERNATIONAL JOURNAL OF MOL. SCI. 23:10 p. 5306 (2022) https://doi.org/10.3390/ijms23105306 D1
Tóth R, Balogh D, Pintér L, Jaksa G, Széplaki B, Gráf A, Györfy Z, Enyedi MZ, Kiss E, Haracska L, Unk I.: The Rad5 Helicase and RING Domains Contribute to Genome Stability through their Independent Catalytic Activities. JOURNAL OF MOL. BIOL. 434:5 Paper: 167437 (2022) https://doi.org/10.1016/j.jmb.2021.167437 D1
Tóth R, Halmai M*, Gyorfy Z, Bálint É, Unk I.: The inner side of yeast PCNA contributes to genome stability by mediating interactions with Rad18 and the replicative DNA polymerase δ. SCIENTIFIC REPORTS 12:1 Paper: 5163 (2022) https://doi.org/10.1038/s41598-022-09208-7 D1

2021

Bajusz, I. Kristó, C. Abonyi, T. Venit, V. Vedelek, T. Lukácsovich, A. Farkas, P. Borkúti, Z. Kovács, I. Bajusz, A. Marton, C. Vizler, Z. Lipinszki, R. Sinka, P. Percipalle, and P. Vilmos, The nuclear activity of the actin‐binding Moesin protein is necessary for gene expression in Drosophila. FEBS JOURNAL, 19 February https://doi.org/10.1111/febs.15779 (2021)
Á. Balog, V. Honti, É. Kurucz, B. Kari, L. G. Puskás, I. Andó, and G. J. Szebeni Immunoprofiling of Drosophila Hemocytes by Single-cell Mass Cytometry. GENOMICS PROTEOMICS & BIOINFORMATICS (2021)
Csordás, E. Gábor, and V. Honti. There and back again: The mechanisms of differentiation and transdifferentiation in Drosophila blood cells, DEVELOPMENTAL BIOLOGY, vol. 469, pp. 135–143 (2021)
Gaur, G. Fenteany, and C. Tyagi. Mode of inhibitory binding of epigallocatechin gallate to the ubiquitin-activating enzyme Uba1 via accelerated molecular dynamics. RSC ADVANCES, vol. 11, no. 14, pp. 8264–8276 (2021)
Laczkó-Dobos, A. K. Maddali, A. Jipa, A. Bhattacharjee, A. G. Végh, and G. Juhász. Lipid profiles of autophagic structures isolated from wild type and Atg2 mutant Drosophila. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, vol. 1866, no. 3 (2021)
Maár, G. Varga, B. Kovács, O. Schütz, Z. Maróti, T. Kalmár, E. Nyerki, I. Nagy, D. Latinovics, B. Tihanyi, A. Marcsik, G. Pálfi, Z. Bernert, Z. Gallina, S. Varga, L. Költő, I. Raskó, T. Török, and E. Neparáczki. Maternal Lineages from 10-11th Century Commoner Cemeteries of Carpathian Basin,GENES, 2021 Mar 23;12(3):460.
Manzéger, K. Tagscherer, P. Lőrincz, H. Szaker, T. Lukácsovich, P. Pliz, R. Kméczik, G. Csikós, M. Erdélyi, M. Sass, T. Kovács, T. Vellai, and V. Billes. Condition-dependent functional shift of two Drosophila Mtmr lipid phosphatases in autophagy control. AUTOPHAGY 2021 Mar 28;1-19 (2021)
Paeschke and P. Burkovics. Mgs1 function at G-quadruplex structures during DNA replication. CURRENT GENETICS 2021 Apr;67(2):225-230 (2021)
Takáts, L. Lévay, A. Boda, S. Tóth, Z. Simon-Vecsei, A. Rubics, Á. Varga, M. Lippai, P. Lőrincz, G. Glatz, and G. Juhász. The Warburg Micro Syndrome- associated Rab3GAP-Rab18 module promotes autolysosome maturation through the Vps34 Complex I. FEBS JOURNAL, vol. 288, no. 1, pp. 190–211 (2021)

2020

Cinege, Gyöngyi; Lerner, Zita; Magyar, Lilla B.;Soós, Bálint;Tóth, Renáta; Kristó, Ildikó;Vilmos, Péter; Juhász, Gábor; Kovács, Attila L.; Hegedűs, Zoltán et al. Cellular Immune Response Involving Multinucleated Giant Hemocytes with Two-Step Genome Amplification in the Drosophilid Zaprionus indianus JOURNAL OF INNATE IMMUNITY 12 : 3 257-272. , 16 p. (2020)
Fenteany, Gabriel; Gaur, Paras; Sharma, Gaurav; Pintér, Lajos; Kiss, Ernő;Haracska, Lajos Robust high-throughput assays to assess discrete steps in ubiquitination and related cascades BMC Molecular and Cell Biology 21 : 1 Paper: 21 (2020)
Kiss, Viktória;Jipa, András ; Varga, Kata ; Takáts, Szabolcs ; Maruzs, Tamás; Lőrincz, Péter; Simon-Vecsei, Zsófia ; Szikora, Szilárd; Földi, István; Bajusz, Csaba et al. Drosophila Atg9 regulates the actin cytoskeleton via interactions with profilin and Ena CELL DEATH AND DIFFERENTIATION 27 : 5 1677-1692. , 16 p. (2020)
Maria Ninova , Baira Godneeva , Yung-Chia Ariel Chen, Yicheng Luo, Sharan J Prakash, Ferenc Jankovics, Miklós Erdélyi, Alexei A Aravin, Katalin Fejes TóthThe SUMO Ligase Su(var)2-10 Controls Hetero- And Euchromatic Gene Expression via Establishing H3K9 Trimethylation and Negative Feedback Regulation MOLECULAR CELL Feb 6;77(3):571-585.e4. (2020)
Szikora, Szilárd; Gajdos,Tamás;Novák, Tibor; Farkas, Dávid; Földi, István ; Lenart, Peter; Erdélyi, Miklós ;Mihály, József Nanoscopy reveals the layered organization of the sarcomeric H-zone and I-band complexes JOURNAL OF CELL BIOLOGY 219 : 1 Paper: e201907026 , 21 p. (2020)

2019

Bajusz I, Henry S, Sutus E, Kovács G, Pirity MK. Evolving Role of RING1 and YY1 Binding Protein in the Regulation of Germ-Cell-Specific Transcription. Genes (Basel).10(11).(2019)
Bhattacharjee, A ; Szabo, A ; Csizmadia, T ; Laczko-Dobos, H ; Juhasz, G Understanding the importance of autophagy in human diseases using Drosophila JOURNAL OF GENETICS AND GENOMICS 46 : 4 pp. 157-169. , 13 p. (2019)
Fenteany, Gabriel ; Gaur, Paras ; Hegedűs, Lili ; Dudás, Kata ; Kiss, Ernő ; Wéber, Edit ; Hackler, László ; Martinek, Tamás ; Puskás, László G. ; Haracska, Lajos. Multilevel structure–activity profiling reveals multiple green tea compound families that each modulate ubiquitin-activating enzyme and ubiquitination by a distinct mechanism SCIENTIFIC REPORTS 9 : 1 Paper: 12801 (2019)
Lőrincz, Péter ; Kenéz, Lili Anna ; Tóth, Sarolta ; Kiss, Viktória ; Varga, Ágnes; Csizmadia, Tamás ; Simon-Vecsei, Zsófia ; Juhász, Gábor. Vps8 overexpression inhibits HOPS-dependent trafficking routes by outcompeting Vps41/Lt ELIFE 8 Paper: e45631 (2019)
Smith, Rebecca ; Lebeaupin, Théo ; Juhasz, Szilvia ; Chapuis, Catherine ; D'Augustin, Ostiane ; Dutertre, Stéphanie ; Burkovics, Peter ; Biertuempfel, Christian ; Timinszky, Gyula ; Huet, SébastienPoly(ADP-ribose)-dependent chromatin unfolding facilitates the association of DNA-binding proteins with DNA at sites of damage Nucleic Acids Res. 47(21):11250-11267 (2019)

2018

Bajusz, C ; Borkuti, P ; Kristo, I ; Kovacs, Z ; Abonyi, C ; Vilmos, P Nuclear actin: ancient clue to evolution in eukaryotes? HISTOCHEMISTRY AND CELL BIOLOGY 150 : 3 pp. 235-244. , 10 p. (2018)
Fajka-Boja, R ; Marton, A ; Tóth, A ; Blazsó, P ; Tubak, V ; Bálint, B ; Nagy, I ; Hegedűs, Z ; Vizler, C ; Katona, RLIncreased insulin-like growth factor 1 production by polyploid adipose stem cells promotes growth of breast cancer cells BMC CANCER 18 Paper: 872 , 12 p. (2018)
Jankovics, Ferenc ; Bence, Melinda ; Sinka, Rita ; Farago, Aniko ; Bodai, Laszlo ; Pettko-Szandtner, Aladar ; Ibrahim, Karam ; Takacs, Zsanett ; Szarka-Kovacs, Alexandra Brigitta ; Erdelyi, MiklosDrosophila small ovary gene is required for transposon silencing and heterochromatin organization, and ensures germline stem cell maintenance and differentiation DEVELOPMENT 145 : 23 Paper: UNSP dev170639 , 13 p. (2018)
Migh, E ; Gotz, T ; Foldi, I ; Szikora, S ; Gombos, R ; Darula, Z ; Medzihradszky, KF ; Maleth, J ; Hegyi, P ; Sigrist, S et al. Microtubule organization in presynaptic boutons relies on the formin DAAMDEVELOPMENT 145 : 6 Paper: dev158519 , 13 p. (2018)
Peng, M ; Cong, K ; Panzarino, NJ ; Nayak, S ; Calvo, J ; Deng, B ; Zhu, LJ ; Morocz, M ; Hegedus, L ; Haracska, L et al. Opposing Roles of FANCJ and HLTF Protect Forks and Restrain Replication during Stress CELL REPORTS 24 : 12 pp. 3251-3261. , 11 p. (2018)

2017

Vig AT, Földi I, Szikora S, Migh E, Gombos R, Tóth MÁ, Huber T, Pintér R, Talián GC, Mihály J, Bugyi B. The activities of the c-terminal regions of the formin protein disheveled-associated activator of morphogenesis (daam) in actin dynamics JOURNAL OF BIOLOGICAL CHEMISTRY 292:(33) pp. 13566-13583. (2017)
Bence M , Jankovics F , Lukacsovich T , Erdelyi M Combining the auxin-inducible degradation system with CRISPR/Cas9-basedgenome editing for the conditional depletion of endogenous Drosophila melanogaster proteins FEBS JOURNAL 284:(7) pp. 1056-1069. (2017)
Cinege G , Zsamboki J , Vidal-Quadras M , Uv A , Csordas G , Honti V ,Gabor E , Hegedus Z , Varga GIB , Kovacs AL , Juhasz G , Williams MJ ,Ando I , Kurucz E Genes encoding cuticular proteins are components of the Nimrod gene cluster in Drosophila. INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY 87: pp. 45-54. (2017)
Gali VK , Balint E , Serbyn N , Frittmann O , Stutz F , Unk I Translesion synthesis DNA polymerase. exhibits a specific RNA extension activity and a transcription-associated function SCIENTIFIC REPORTS 7: Paper 13055. 17 p. (2017)
Takacs Z , Jankovics F , Vilmos P , Lenart P , Roper K , Erdelyi M The spectraplakin short stop is an essential microtubule regulator involved in epithelial closure in Drosophila. JOURNAL OF CELL SCIENCE 130:(4) pp. 712-724. (2017)

2016

Burkovics P , Dome L , Juhasz S , Altmannova V , Sebesta M , Pacesa M ,Fugger K , Sorensen CS , Lee MY , Haracska L , Krejci L. The PCNA-associated protein PARI negatively regulates homologousrecombination via the inhibition of DNA repair synthesis. NUCLEIC ACIDS RESEARCH 44:(7) pp. 3176-3189. (2016)
Enyedi MZ , Jaksa G , Pinter L , Sukosd F , Gyuris Z , Hajdu A ,Hatarvolgyi E , Priskin K , Haracska L Simultaneous detection of BRCA mutations and large genomic rearrangements in germline DNA and FFPE tumor samples. ONCOTARGET 7:(38) pp. 61845-61859. (2016)
Fajka-Boja R , Urban VS , Szebeni GJ , Czibula A , Blasko A , Kriston-Pal E , Makra I , Hornung A, Szabo E , Uher F , Than NG , Monostori E Galectin-1 is a local but not systemic immunomodulatory factor in mesenchymal stromal cells. CYTOTHERAPY 18:(3) pp. 360-370. (2016)
Kovacs G , Szabo V , Pirity MK Absence of Rybp Compromises Neural Differentiation of Embryonic Stem Cells. STEM CELLS INTERNATIONAL 2016: p. 4034620. (2016)
Vilmos P , Kristó I , Szikora S , Jankovics F , Lukácsovich T , Kari B ,Erdélyi M The actin-binding ERM protein Moesin directly regulates spindle assembly and function during mitosis CELL BIOLOGY INTERNATIONAL 40:(6) pp. 696-707. (2016)

Institute of Plant Biology

2023

Agrawal R, Singh A, Giri J, Magyar Z, Thakur JK. (2023) MEDIATOR SUBUNIT17 is required for transcriptional optimization of root system architecture in Arabidopsis, Plant Physiology, 192(2): 1548-1568. https://doi.org/10.1093/plphys/kiad129 D1
Devadasu ED, Kanna SD, Neelam S, Yadav RM, Nama S, Akhtar P, Polgár TF, Ughy B, Garab G, Lambrev PH and Subramanyam R. (2023) Long- and short-term acclimation of the photosynthetic apparatus to salinity in Chlamydomonas reinhardtii. The role of Stt7 protein kinase. Frontiers in Plant Science, 14: 1051711. https://doi.org/10.3389/fpls.2023.1051711 D1
Fehér A. (2023) A Common Molecular Signature Indicates the Pre-Meristematic State of Plant Calli. Int. J. Mol. Sci. 24(17): 13122. https://doi.org/10.3390/ijms241713122 D1
Garab G, Magyar M, Sipka G and Lambrev PH. (2023) New foundations for the physical mechanism of variable chlorophyll a fluorescence. Quantum efficiency versus the light-adapted state of photosystem II. J Exp Bot. 2023 Sep 29;74(18):5458-5471. doi: 10.1093/jxb/erad252. PMID: 37410874 D1
Gitau MM, Shetty P and Maróti G. (2023) Transcriptional analysis reveals induction of systemic resistance in tomato treated with Chlorella microalgae, Algal Research – Biomass Biofuels and Bioproducts, 72: 103106. https://doi.org/10.1016/j.algal.2023.103106 Q1
Gombos M, Raynaud C, Nomoto Y, Molnár E, Brik-Chaouche R, Takatsuka H, Zaki A, Bernula D, Latrasse D, Mineta K, Nagy F, He X, Iwakawa H, Őszi E, An J, Suzuki T, Papdi C, Bergis C, Benhamed M, Bögre L, Ito M, Magyar Z. The canonical E2Fs together with RETINOBLASTOMA-RELATED are required to establish quiescence during plant development. Commun Biol. 2023 Sep 4;6(1):903. doi: 10.1038/s42003-023-05259-2. PMID: 37666980. D1
Horváth B, Güngör B, Tóth M, Domonkos Á, Ayaydin F, Saifi F, Chen Y, Bíró JB, Bourge M, Szabó Z, Tóth R, Chen R and Kaló P. (2023) The Medicago truncatula nodule-specific cysteine-rich peptides, NCR343 and NCR-new35 are required for the maintenance of rhizobia in nitrogen-fixing nodules, New Phytologist, 239(5): 1974-1988. https://doi.org/10.1111/nph.19097 D1
Magyar M, Sipka G, Han W, Li X, Han G, Shen J-R, Lambrev PH and Garab G. (2023) Characterization of the rate-limiting steps in the dark-to-light transitions of closed Photosystem II. Temperature dependence and invariance of waiting times during multiple light reactions, Int. J. Mol. Sci. 2023, 24(1), 94; https://doi.org/10.3390/ijms24010094 D1
Milrad Y, Nagy V, Elman T, Fadeeva M, Tóth SZ, Yacoby I. (2023) A PSII photosynthetic control is activated in anoxin cultures of green algae following illumination, Communications Biology, 6(1):514.https://doi.org/10.1038/s42003-023-04890-3 D1
Mohamad Aslam S, Vass I and Szabó M. (2023) Characterization of the flash-induced fluorescence wave phenomenon in the coral Endosymbiont algae, Symbiodiniaceae. International Journal of Molecular Sciences, 24 (10): 8712.
https://doi.org/10.3390/ijms24108712 D1
Nagy B, Öktem A, Ferenc G, Ungor D, Kalac A, Kelemen-Valkony I, Fodor E, Nagy I, Dudits D and Ayaydin F. (2023) CRISPR/Cas9 Mutagenesis through Introducing a Nanoparticle Complex Made of a Cationic Polymer and Nucleic Acids into Maize Protoplasts. Int J Mol Sci. 2023 Nov 9;24(22):16137. doi: 10.3390/ijms242216137. PMID: 38003326; PMCID: PMC10671792. D1
Rani V, Maróti G. (2023) Light-Dependent Nitrate Removal Capacity of Green Microalgae.
Int. J. Mol. Sci. 2023, 24(1), 77; https://doi.org/10.3390/ijms24010077 D1
Tóth SZ. (2023)The Functions of Chloroplastic Ascorbate in Vascular Plants and Algae , Int. J. Mol. Sci. 24(3): 2537. https://doi.org/10.3390/ijms24032537 D1
Ughy B, Nagyapáti S, Lajkó DB, Letoha T, Prohaszka A, Deeb D, Dé, A, Pettkó-Szandtner A and Szilák L (2023) Reconsidering dogmas about the growth of bacterial populations, Cells. 12(10): 1430. https://doi.org/10.3390/cells12101430 Q1
van Stokkum IHM, Akhtar P, Biswas A and Lambrev PH. (2023) Energy transfer from phycobilisomes to photosystem I at 77 K. Front Plant Sci. 2023 Nov 22;14:1293813. doi: 10.3389/fpls.2023.1293813. PMID: 38078099; PMCID: PMC10702739. D1
Vidal-Meireles A, Kuntam S, Széles E, TóthD, Neupert J, Bock R and Tóth SZ. (2023) The lifetime of the oxygen-evolving complex subunit PSBO depends on light intensity and carbon availability in Chlamydomonas Plant Cell Environ. 46: 422-439. https://doi.org/10.1111/pce.14481 D1
Wirth R, Bagi Z, Shetty P, Szuhaj M, Cheung TS, Kovács KL and Maróti G. (2023) Inter-kingdom interactions and stability of methanogens revealed by machine-learning guided multi-omics analysis of industrial-scale biogas plants. ISME Journal, 17(8): 1326-1339.
https://doi.org/10.1038/s41396-023-01448-3 D1
Zhang R, Shen Y, He J, Zhang C, Ma Y, Sun C, Son X, Li L, Zhang S, Biró JB, Saifi F, Kalo P, Chen R. (2023) Nodule-Specific Cysteine-Rich Peptide 343 is required for symbiotic nitrogen fixation in Medicago truncatula. Plant Physiology, 193(3):1897-1912. doi: 10.1093/plphys/kiad454. PMID: 37555448. D1
Zhang S, Wang T, Lima R, Pettkó-Szandtner A, Kereszt A, Downie JA and Kondorosi É. (2023) Widely conserved AHL transcription factors are essential for NCR gene expression and nodule development in Medicago. Nature Plants, 9(2): 280-288. https://doi.org/10.1038/s41477-022-01326-4 D1
Zombori Z, Török S, Nagy B, László N, Sass L, Jancsó M, Szabó,G, Rádi F, Ferenc G, Gyuricza C and Dudits D. (2023) Expression of triploid heterosis in the biomass productivity of energy willow plants under salinity stress. Biomass & Bioenergy, 176: 106852.
https://doi.org/10.1016/j.biombioe.2023.106852 D1

2022

Akhtar P, Biswas A, Balog-Vig F, Domonkos I, Kovács L, Lambrev PH. (2022) Trimeric Photosystem I facilitates energy transfer from phycobilisomes in Synechocystis sp. PCC 6803. Plant Physiol. 189(2):827-838. https://doi.org/10.1093/plphys/kiac130 D1
Alvarez ME, Savouré A, Szabados L. (2022) Proline metabolism as regulatory hub, Trends in Plant Science, 27 (1): 39-55. https://doi.org/10.1016/j.tplants.2021.07.009 D1
Bashir F, Kovács S, Ábrahám Á, Nagy K, Ayaydin F, Valkony-Kelemen I, Ferenc G, Galajda P, Tóth SZ, Sass L, Kós PB, Vass I and Szabó M. (2022) Viable protoplast formation of the coral endosymbiont alga Symbiodinium spp. in a microfluidics platform, LAB ON A CHIP, 22(16):2986-2999. https://doi.org/10.1039/D2LC00130F Q1
Benkő P, Gémes K and Fehér A. (2022) Polyamine Oxidase-Generated Reactive Oxygen Species in Plant Development and Adaptation: The Polyamine Oxidase-NADPH Oxidase Nexus. Antioxidants (Basel) 2022 Dec 17;11(12):2488. https://doi.org/10.3390/antiox11122488 D1
Dudits D, Cseri A, Török K, Sass L, Zombori Z, Ferenc G, Poór P, Borbély P, Czékus Z, Vankova R, Dobrev P, Szántó J, Bagi Z and Kovács KL. (2022) Triploid Hybrid Vigor in Above-Ground Growth and Methane Fermentation Efficiency of Energy Willow. Frontiers in Plant Science, 13: 770284 https://doi.org/10.3389/fpls.2022.770284 D1
Farago D, Zsigmond L, Benyo D, Alcazar R, Rigo G, Ayaydin F, Rabilu SA. and Szabados L. (2022) Small paraquat resistance proteins modulate paraquat and ABA responses and confer drought tolerance to overexpressing Arabidopsis plants, PLANT CELL AND ENVIRONMENT, ; 45(7):1985-2003. https://doi.org/10.1111/pce.14338. D1
Gitau MM, Farkas A, Ördög V and Maróti G. (2022) Evaluation of the biostimulant effects of two Chlorophyta microalgae on tomato (Solanum lycopersicum), Journal of Cleaner Production, 364: 132689, https://doi.org/10.1016/j.jclepro.2022.132689. D1
Gulyás Z, Moncsek B, Hamow KÁ, Stráner P, Tolnai Z, Badics E, Incze N, Darkó É, Nagy V, Perczel A, Kovács L and Soós V. (2022) D27‐LIKE1 isomerase has a preference towards trans/cis and cis/cis conversions of carotenoids in Arabidopsis, Plant Journal, 112: 1377 – 1395.
https://doi.org/10.1111/tpj.16017 D1
Kanygin A, Smith A, Nagy V, Tóth SZ and Redding KE. (2022) Interplay between hydrogen production and photosynthesis in a green alga expressing an active photosystem I-hydrogenase chimera, International Journal of Hydrogen Energy, 47(52): 21969-21983.
https://doi.org/10.1016/j.ijhydene.2022.03.096 Q1
Lakatos L, Groma G, Silhavy D, Nagy F. (2022) In Arabidopsis thaliana, RNA-Induced Silencing Complex-Loading of MicroRNAs Plays a Minor Regulatory Role During Photomorphogenesis Except for miR163. Front Plant Sci. 13:854869. https://doi.org/10.3389/fpls.2022.854869 D1
Lima RM, Rathod BB, Tiricz H, Howan DHO, Al Bouni MA, Jenei S, Tímár E, Endre G, Tóth GK and Kondorosi É (2022) Legume Plant Peptides as Sources of Novel Antimicrobial Molecules Against Human Pathogens. Front. Mol. Biosci. 9:870460. https://doi.org/10.3389/fmolb.2022.870460
Q1
Liu J, Wang T, Qin Q, Yu X, Yang S, Dinkins RD, Kuczmog A, Putnoky P, Muszyński A, Griffitts JS, Kereszt A, Zhu H. (2022) Paired Medicago receptors mediate broad-spectrum resistance to nodulation by Sinorhizobium meliloti carrying a species-specific gene. Proc Natl Acad Sci U S A. 119(51):e2214703119. https://doi.org/10.1073/pnas.2214703119 D1
Nomoto Y, Takatsuka H, Yamada K, Suzuki T, Suzuki T, Huang Y, Latrasse D, An J, Gombos M, Breuer C, Ishida T, Maeo K, Imamura M, Yamashino T, Sugimoto K, Magyar Z, Bögre L, Raynaud C, Benhamed M and Ito M. (2022) A hierarchical transcriptional network activates specific CDK inhibitors that regulate G2 to control cell size and number in Arabidopsis, Nature Communications, 13 (1): 1660. https://doi.org/10.1038/s41467-022-29316-2 D1
Patil PP, Vass I and Szabó M. (2022) Characterization of the Wave Phenomenon in Flash-Induced Fluorescence Relaxation and Its Application to Study Cyclic Electron Pathways in Microalgae, International Journal of Molecular Sciences, 2022, 23(9), 4927; https://doi.org/10.3390/ijms23094927 D1
Pleckaitis M, Habach F, Kontenis L, Steinbach G, Jarockyte G, Kalnaityte A, Domonkos I, Akhtar P, Alizadeh M, Bagdonas S, Karabanovas V, Garab G, Rotomskis R and Barzda V. (2022) Structure and principles of self-assembly of giant "sea urchin" type sulfonatophenyl porphine aggregates, NANO RESEARCH, 15: 5527-5537.https://doi.org/10.1007/s12274-021-4048-x D1
Riyazuddin R, Bela K, Poór P, Szepesi Á, Horváth E, Rigó G, Szabados L, Fehér A and Csiszár J. (2022) Crosstalk between the Arabidopsis Glutathione Peroxide-like 5 isoenzyme (AtGPXL5) and Ethylene. Int. J. Mol. Sci. 2022, 23(10), 5749; https://doi.org/10.3390/ijms23105749 D1
Sipka G, Nagy L, Magyar M, Akhtar P, Shen J-R, Holzwarth AR, Lambrev PH, Garab G. (2022) Light-induced reversible reorganizations in closed Type II reaction centre complexes: physiological roles and physical mechanisms. Open Biol. 12: 220297. https://doi.org/10.1098/rsob.220297 D1
Szádeczky-Kardoss,I*, Szaker HM*, Verma R, Darkó É, Pettkó-Szandtner A, Silhavy D and Csorba T. (2022) Elongation factor TFIIS is essential for heat stress adaptation in plants, NUCLEIC ACIDS RESEARCH (2022) 50(4): 1927-1950. https://doi.org/10.1093/nar/gkac020 D1
Széles E, Nagy K, Ábrahám Á, Kovács S, Podmaniczki A, Nagy V, Kovács L, Galajda P and Tóth SZ. (2022) Microfluidic Platforms Designed for Morphological and Photosynthetic Investigations of Chlamydomonas reinhardtii on a Single-Cell Level. CELLS 11(2): 285. (2022)
https://doi.org/10.3390/cells11020285n Q1
Wang T, Balla B, Kovács S, Kereszt A. (2022) Varietas Delectat: Exploring Natural Variations in Nitrogen-Fixing Symbiosis Research. Front Plant Sci. 13:856187. https://doi.org/10.3389/fpls.2022.856187. D1

2021

Andrási, N.; Pettkó-Szandtner, A.; Szabados, L.: Diversity of plant heat shock factors: regulation, interactions, and functions, Journal of Experimental Botany, 72: 5, 1558-1575, https://doi.org/10.1093/jxb/eraa576 (2021)
Bernula, P.; Pettkó-Szandtner, A.; Hajdu, A.; Kozma-Bognár, L.; Josse, E.-M.; Ádám, É.; Nagy, F.; Viczián, A.: SUMOylation of PHYTOCHROME INTERACTING FACTOR 3 promotes photomorphogenesis in Arabidopsis thaliana, New Phytologist, 229: 2050-2061. https://doi.org/10.1111/nph.17013 (2021)
Dragos, A.; Priyadarshini, B.; Hasan, Z.; Strube, M.L.; Kempen, P.J.; Maroti, G.; Kaspar, C.; Bose, B.; Burton, B.M.; Bischofs, I.B.; Kovacs, A.T.: Pervasive prophage recombination occurs during evolution of spore-forming Bacilli, ISME JOURNAL, DOI:1038/s41396-020-00854-1 (2021)
Knisz, J.; Shetty, P.; Wirth, R.; Maróti, G.; Karches, T.; Dalkó, I.; Bálint, M.; Vadkerti, E.; Bíró, T.: Genome-level insights into the operation of an on-site biological wastewater treatment unit reveal the importance of storage time. Science of the Total Environment, 766: 144425. https://doi.org/10.1016/j.scitotenv.2020.144425 (2021)
Podmaniczki, A.; Nagy, V.; Vidal-Meireles, A.; Tóth, D.; Patai, R.; Kovács, L.; Toth, S.Z.: Ascorbate inactivates the oxygen-evolving complex in prolonged darkness. PhysiologiaPlantarum, 171: 232–245. https://doi.org/10.1111/ppl.13278 (2021)
Sipka, G.; Magyar, M.; Mezzetti, A.; Akhtar, P.; Zhu, Q.; Xiao, Y.; Han, G.; Santabarbara, S.; Shen, J.-R.; Lambrev, P.H.; Garab, G.: Light-Adapted Charge-Separated State of Photosystem II: Structural and Functional Dynamics of the Closed Reaction Center, The Plant Cell, koab008, https://doi.org/10.1093/plcell/koab008 (2021)

2020

Choi, S.W.; Ryu, M.Y.; Viczián, A.; Jung, H.J.; Kim, G.M.; Arce, A.L.; Achkar, N.P.; Manavella, P.; Dolde, U.; Wenkel, S.; Molnár, A.; Nagy, F.; Cho, S.K.; Yang, S.W.: Light triggers the miRNA-biogenetic inconsistency for de-etiolated seedling survivability in Arabidopsis thaliana. MOLECULAR PLANT, 13: 3, pp. 431-445. doi: 10.1016/j.molp.2019.10.011. (2020)
Mergaert, P.; Kereszt, A.; Kondorosi, É.: Gene expression in nitrogen-fixing symbiotic nodule cells in Medicago truncatula and other nodulating plants. PLANT CELL, 32: 1, pp. 42-68. (2020)
Őszi, E.; Papdi, C.; Mohammed, B.; Pettkó-Szandtner, A.; Vaskó-Leviczky, T.; Molnár, E.; Galvay-Ampudia, C.; Khan, S.; Lopez-Juez, E.; Horváth, B.; Bögre, L.; Magyar, Z.: E2FB interacts with RETINOBLASTOMA RELATED and regulates cell proliferation during leaf development. PLANT PHYSIOLOGY, 182: 1, pp. 518-533. (2020)
Viczián, A.; Ádám, É.; Staudt, A.M.; Lambert, D.; Klement, É.; Romero Montepaone, S.; Hiltbrunner, A.; Casal, J.; Schafer, E.; Nagy, F.; Klose, C.: Differential phosphorylation of the N-terminal extension regulates phytochrome B signaling. NEW PHYTOLOGIST, 225: pp. 1635-1650. (2020)
Vidal-Meireles, A.; Tóth, D.; Kovács, L.; Neupert, J.; Toth, S.Z.: Ascorbate deficiency does not limit non-photochemical quenching in Chlamydomonas reinhardtii. PLANT PHYSIOLOGY, 182: 1, pp. 597-611. (2020)
Choi, S.W.; Ryu, M.Y.; Viczián, A.; Jung, H.J.; Kim, G.M.; Arce, A.L.; Achkar, N.P.; Manavella, P.; Dolde, U.; Wenkel, S.; Molnár, A.; Nagy, F.; Cho, S.K.; Yang, S.W.: Light triggers the miRNA-biogenetic inconsistency for de-etiolated seedling survivability in Arabidopsis thaliana. MOLECULAR PLANT, 13: 3, pp. 431-445. https://doi: 10.1016/j.molp.2019.10.011. (2020)
De Luxán-Hernández, C.; Lohmann, J.; Hellmeyer, W.; Seanpong, S.; Wöltje, K.; Magyar, Z.; Pettkó-Szandtner, A.; Pélissier, T.; De Jaeger, G.; Hoth, S.; Mathieu, O.; Weingartner, M.: PP7L is essential for MAIL1-mediated TE silencing and primary root growth. PLANT JOURNAL, 102: 4, pp. 703-717. https://doi.org/10.1111/tpj.14655 (2020)
Jánosi, I.M.; Silhavy, D.; Tamás, J.; Csontos, P.: Bulbous perrenials precisely detect the length of winter and adjust flowering dates, NEW PHYTOLOGIST, 228: 5, pp. 1535-1547. https://doi.org/10.1111/nph.16740 (2020)
Martin, M.; Dragos, A.; Otto, S.B.; Schafer, D.; Brix, S.; Maróti, G.; Kovács, Á.T.: Cheaters shape the evolution of phenotypic heterogeneity in Bacillus subtilis biofilms, ISME JOURNAL, 14(9): 2302-2312. https://doi.org/10.1038/s41396-020-0685-4 (2020)
Mergaert, P.; Kereszt, A.; Kondorosi, É.: Gene expression in nitrogen-fixing symbiotic nodule cells in Medicago truncatula and other nodulating plants. THE PLANT CELL, 32: 1, pp. 42-68. https://doi.org/10.1105/tpc.19.00494 (2020)
Őszi, E.; Papdi, C.; Mohammed, B.; Pettkó-Szandtner, A.; Vaskó-Leviczky, T.; Molnár, E.; Galvay-Ampudia, C.; Khan, S.; Lopez-Juez, E.; Horváth, B.; Bögre, L.; Magyar, Z.: E2FB interacts with RETINOBLASTOMA RELATED and regulates cell proliferation during leaf development. PLANT PHYSIOLOGY, 182: 1, pp. 518-533. https://doi.org/10.1104/pp.19.00212 (2020)
Sós‐Hegedűs, A.; Domonkos, Á.; Tóth, T.; Gyula, P.; Kaló, P.; Szittya, G.: Suppression of NB‐LRR Genes by miRNAs Promotes Nitrogen‐fixing Nodule Development in Medicago truncatula, Plant Cell and Environment, 43: 5, pp. 1117-1129. https://doi.org/10.1111/pce.13698 (2020)
Viczián, A.; Ádám, É.; Staudt, A.M.; Lambert, D.; Klement, É.; Romero Montepaone, S.; Hiltbrunner, A.; Casal, J.; Schafer, E.; Nagy, F.; Klose, C.: Differential phosphorylation of the N-terminal extension regulates phytochrome B signaling. NEW PHYTOLOGIST, 225: pp. 1635-1650. https://doi.org/10.1111/nph.16243 (2020)
Vidal-Meireles, A.; Tóth, D.; Kovács, L.; Neupert, J.; Toth, S.Z.: Ascorbate deficiency does not limit non-photochemical quenching in Chlamydomonas reinhardtii. PLANT PHYSIOLOGY, 182: 1, pp. 597-611. https://doi.org/10.1104/pp.19.00916 (2020)
Walton, J.H.; Kontra-Kovats, G.; Green, R.T.; Domonkos,

2019

Andrási, N.; Rigó, G.; Zsigmond, L.; Pérez-Salamó, I.; Papdi, C.; Klement, E.; Baba, A.I.; Ayaydin, F.; Dasari, R.; Cséplő, Á.; Szabados, L.: The MPK4-phosphorylated Heat Shock Factor A4A regulates responses to combined salt and heat stresses. JOURNAL OF EXPERIMENTAL BOTANY, 70: 18, pp. 4903-4918. (2019)
Liu, C.W.; Breakspear, A.; Stacey, N.; Findlay, K.; Nakashima, J.; Ramakrishnan, K.; Liu, M.; Xie, F.; Endre, G.; de Carvalho-Niebel, F.; Oldroyd, G.E.D.; Udvardi, M.K.; Fournier, J.; Murray, J.D.: A protein complex required for polar growth of rhizobial infection threads. NATURE COMMUNICATIONS, 10: 1, pp. 2848, doi: 10.1038/s41467-019-10029-y. (2019
Tóth, S.Z.; Yacoby, I.: Paradigm shift in algal H2 production: Bypassing competitive processes. TRENDS IN BIOTECHNOLOGY, 37: 11, pp. 1159-1163. (2019)
Ughy, B.; Schmidthoffer, I.; Szilak, L: Heparan sulfate proteoglycan (HSPG) can take part in cell division: inside and outside. CELLULAR AND MOLECULAR LIFE SCIENCES, 76: 5, pp. 865-871. (2019)
Vanhaelewyn, L.; Viczián, A.; Prinsen, E.; Bernula, P.; Serrano, A.M.; Arana, M.V.; Ballaré, C.L.; Nagy, F.; Van Der Straeten, D.; Vandenbussche, F.: Differential UVR8 signal across the stem controls UV-B-induced inflorescence phototropism. PLANT CELL, 31: 9, pp. 2070-2088. (2019)

2018

Dragoš, A.; Martin, M.; Garcia, C.F.; Kricks, L.; Pausch, P.; Heimerl, T.; Bálint, B.; Maróti, G.; Bange, G.; López, D.; Lieleg, O.; Kovács, Á.T.: Collapse of genetic division of labour and evolution of autonomy in pellicle biofilms. NATURE MICROBIOLOGY, 3: 12, pp. 1451-1460. (2018)
Hajdu, A.; Dobos, O.; Domijan, M.; Bálint, B.; Nagy, I.; Nagy, F.; Kozma-Bognár, L.: ELONGATED HYPOCOTYL 5 mediates blue light signaling to the Arabidopsis circadian clock. PLANT JOURNAL, 96: 6, pp. 1242-1254. (2018)
Magyar, M.; Sipka, G.; Kovacs, L.; Ughy, B.; Zhu, Q.; Han, G.; Spunda, V.; Lambrev, P.H.; Shen, J.-R.; Garab, G.: Rate-limiting steps in the dark-to-light transition of Photosystem II - revealed by chlorophyll-a fluorescence induction. SCIENTIFIC REPORTS, 8: 1, pp. 2755. DOI: 10.1038/s41598-018-21195-2(2018)
Natan, E.; Endoh, T.; Haim-Vilmovsky, L.; Flock, T.; Chalancon, G.; Hopper, J.T.S.; Kintses, B.; Horváth, P.; Daruka, L.; Fekete, G.; Pál, C.; Papp, B.; Oszi, E.; Magyar, Z.; , Marsh, J.A.; Elcock, A.H.; Babu, M.M.; Robinson, C.V.; Sugimoto, N.; Teichmann, S.A.: Cotranslational protein assembly imposes evolutionary constraints on homomeric proteins. NATURE STRUCTURAL & MOLECULAR BIOLOGY, 25: 3, pp. 279-288. (2018)
Tóth, S.Z.; Lőrincz, T.; Szarka, A. : Concentration does matter: The beneficial and potentially harmful effects of ascorbate in humans and plants, ANTIOXIDANTS & REDOX SIGNALING, 29: 15, pp. 1516-1533. (2018)

2017

Bersanini, L.; Allahverdiyeva, Y.; Battchikova, N.; Heinz, S.; Lespinasse, M.; Ruohisto, E.; Mustila, H.; Nickelsen, J.; Vass, I.; Aro, E.-M.: Dissection the photoprotective mechanism encoded by the flv4-2 operon: a distinct contribution of sll0218 in photosystem II stabilization, PLANT CELL & ENVIRONMENT, 40: 3, pp. 378-389. (2017)
Eyal, B.L.; Choubeh, R.R.; Cohen, E.; Eisenberg, I.; Tamburu, C.; Dorogi, M.; Ünnep, R.; Appavouh, M.-S.; Nevoi, R.; Ravive, U.; Reichi, Z.; Garab, G.; van Amerongen, H.; Paltiel, Y.; Kerena, N.: Changes in aggregation states of light-harvesting complexes as a mechanism for modulating energy transfer in desert crust cyanobacteria, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 114: 35, pp. 9481-9486. (2017)
Horvath, B.M.; Kourova, H.; Nagy, S.; Nemeth, E.; Magyar, Z.; Papdi, C.;(16, Pettkó-Szandtner A): Arabidopsis RETINOBLASTOMA RELATED directly regulates DNA damage responses through functions beyond cell cycle control. EMBO JOURNAL, 36: 9, pp.1261-1278. (2017)
Nyikó, T.; Auber, A.; Szabadkai, L.; Benkovics, A.; Auth, M.; Mérai, Z.; Kerényi, Z.; Dinnyés, A.; Nagy, F.; Silhavy, D.: Expression of the eRF1 translation termination factor is controlled by an autoregulatory circuit involving readthrough and nonsense-mediated decay in plants. NUCLEIC ACIDS RESEARCH, 45: 7, pp. 4174-4188. (2017)
Vidal-Meireles, A.; Neupert, J.; Zsigmond, L.; Rosado-Souza, L.; Kovács, L.; Nagy, V.;(10, Galambos A, Tóth, S.Z.: Regulation of ascorbate biosynthesis in green algae has evolved to enable rapid stress-induced response via the VTC2 gene encoding GDP-L-galactose phosphorylase. NEW PHYTOLOGIST, 214: 2, pp. 668-681 (2017)

2016

Dudits, D.; Török, K.; Cseri, A.; Paul, K.; Nagy, A.V.; Nagy, B.; Sass, L.; Ferenc, G.; Vankova, R.; Dobrev, P.; Vass, I.; Ayaydin; F.: Response of organ structure and physiology to autotetraploidization in early development of energy willow Salix viminalis L. PLANT PHYSIOLOGY, 170: 3, pp. 1504-1523. (2016)
Herdean, A.; Teardo, E.; Nilsson, A.K.; Pfeil, B.E.; Johansson, O.N.; Ünnep, R.; Nagy, G.; Zsiros, O.; Dana, S.; Solymosi, K.; Garab, G.; Szabó, I.; Spetea, C.; Lundin, B.: A voltage-dependent chloride channel fine-tunes photosynthesis in plants. NATURE COMMUNICATIONS, 7: pp. 11654. doi: 10.1038/ncomms11654. (2016)
Kirchenbauer, D.; Viczián, A.;, Ádám, É.;, Hegedűs, Z.; Klose, C.; Leppert, M.; Hiltbrunner, A.; Kircher, S.; Schaefer, E.; Nagy, F.: Characterization of photomorphogenic responses and signaling cascades controlled by phytochrome-A expressed in different tissues. NEW PHYTOLOGIST, 211: 2, pp. 584-598. (2016)
Nielsen, J.T.; Kulminskaya, N.V.; Bjerring, M.; Linnanto, J.M.; Rätsep, M.; Pedersen, M.Ø.; Lambrev, P.H.; Dorogi, M.; Garab, G.; Thomsen, K.; Jegerschöld, C.; Frigaard, N.-U.; Lindhal, M.; Nielsen, N. Chr.: In situ high-resolution structure of the baseplate antenna complex in Chlorobaculum tepidum. NATURE COMMUNICATIONS, 7: pp. 12454. https://doi.org/10.1038/ncomms12454 (2016)
Rehman, A.U.; Szabó, M.; Deák, Z.; Sass, L.; Larkum, A.; Ralph, P.; Vass, I.: Symbiodinium sp. cells produce light induced intra- and extra-cellular singlet oxygen, which mediates photodamage of the photosynthetic apparatus and has the potential to interact with the animal host in coral symbiosis. NEW PHYTOLOGIST, 212: 2, pp. 472-484. (2016)